BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients' outcome. - Wikidata - awgldk - TriplyDB

BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients' outcome.

BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients' outcome.

http://www.wikidata.org/entity/Q33906044

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Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer.BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications BRAF mutations in advanced cancers: clinical characteristics and outcomes BRAF p.Val600Glu (V600E) Testing for Assessment of Treatment Options in Metastatic Colorectal Cancer.Impact of KRAS, BRAF, PIK3CA mutations, PTEN, AREG, EREG expression and skin rash in ≥ 2 line cetuximab-based therapy of colorectal cancer patients A very low incidence of BRAF mutations in Middle Eastern colorectal carcinoma.Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN, and FOCUS studies.Mutation profiling and microsatellite instability in stage II and III colon cancer: an assessment of their prognostic and oxaliplatin predictive value BRAFV600E mutation analysis in patients with metastatic colorectal cancer (mCRC) in daily clinical practice: correlations with clinical characteristics, and its impact on patients' outcome.Prognostic significance of cyclin D1 expression in colorectal cancer: a meta-analysis of observational studies.Association of the colorectal CpG island methylator phenotype with molecular features, risk factors, and family history Cancer immunology--analysis of host and tumor factors for personalized medicine.Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803 BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.Clinico-pathological nomogram for predicting BRAF mutational status of metastatic colorectal cancer.Mutation-specific antibody detects mutant BRAFV600E protein expression in human colon carcinomas.Biomarker in Colorectal Cancer.Metastatic colorectal cancer first-line treatment with bevacizumab: the impact of K-ras mutation.Clinical meaning of BRAF mutation in Korean patients with advanced colorectal cancer Systematic review of pharmacogenetic testing for predicting clinical benefit to anti-EGFR therapy in metastatic colorectal cancer.BRAF mutation is associated with distinct clinicopathological characteristics in colorectal cancer: a systematic review and meta-analysis.Current opinion on optimal systemic treatment for metastatic colorectal cancer: outcome of the ACTG/AGITG expert meeting ECCO 2013.The distinctive molecular, pathological and clinical characteristics of BRAF-mutant colorectal tumors.BRAF in metastatic colorectal cancer: the future starts now.Update on optimal treatment for metastatic colorectal cancer from the ACTG/AGITG expert meeting: ECCO 2015.BRAF inhibitor treatment of melanoma causing colonic polyps: An alternative hypothesis.Role of NRAS mutations as prognostic and predictive markers in metastatic colorectal cancer.p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers.Wnt/β-catenin pathway activation mediates adaptive resistance to BRAF inhibition in colorectal cancer.High-frequency microsatellite instability and BRAF mutation (V600E) in unselected Serbian patients with colorectal cancer.The BRAF mutation is associated with the prognosis in colorectal cancer.Colorectal cancer genomics and designing rational trials.'Monster cell' melanoma with pulmonary metastasis and cyclin D1 amplification Prognostic value of the combination of microsatellite instability and mutation in colorectal cancer

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P2860

BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients' outcome.

http://www.wikidata.org/entity/Q33906044

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Detection of BRAF V600E mutation in colorectal cancer: comparison of automatic sequencing and real-time chemistry methodology

Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer.

Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

Mutations of the BRAF gene in human cancer

Front-line bevacizumab in combination with oxaliplatin, leucovorin and 5-fluorouracil (FOLFOX) in patients with metastatic colorectal cancer: a multicenter phase II study

Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

Systematic review of microsatellite instability and colorectal cancer prognosis

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