CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383.
about
Genetic contribution to osteoarthritis development: current state of evidenceFunctional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11-A Bioinformatics and Molecular StudyIncreased DNA Methylation and Reduced Expression of Transcription Factors in Human Osteoarthritis Cartilage.A consistent and potentially exploitable response during chondrogenesis of mesenchymal stem cells from osteoarthritis patients to the protein encoded by the susceptibility gene GDF5Genetic influence of growth and differentiation factor 5 gene polymorphism (+104T/C) on the development of knee osteoarthritis and its association with disease severityGenetic-epigenetic interactions in cis: a major focus in the post-GWAS eraAssociation between EN1 rs4144782 and susceptibility of knee osteoarthritis: A case-control study.Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.Emerging targets in osteoarthritis therapy.Role of Specificity Protein-1 and Activating Protein-2 Transcription Factors in the Regulation of the Gap Junction Protein Beta-2 Gene in the Epididymis of the Rat.Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic riskIdentification of differentially methylated regions in new genes associated with knee osteoarthritis.Association study between growth differentiation factor 5 polymorphism and non-contact anterior cruciate ligament rupture in Chinese Han population.Genetic Contribution to the Development of Radiographic Knee Osteoarthritis in a Population Presenting with Nonacute Knee Symptoms a Decade EarlierTGF-β signal transduction pathways and osteoarthritis.Epigenetics of osteoarticular diseases: recent developments.A comprehensive meta-analysis of association between genetic variants of GDF5 and osteoarthritis of the knee, hip and hand.DNA Methylation in Osteoarthritis.ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity.Why location matters - site-specific factors in rheumatic diseases.Transcriptional associations of osteoarthritis-mediated loss of epigenetic control in articular cartilage.Growth without growth hormone: can growth and differentiation factor 5 be the mediator?Genome Engineering for Personalized Arthritis Therapeutics.Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis.Who or what controls tendon?Interplay between genetic and epigenetic mechanisms in rheumatoid arthritis.Combined bioinformatics analysis reveals gene expression and DNA methylation patterns in osteoarthritis.
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P2860
CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
CpG methylation regulates alle ...... s susceptibility SNP rs143383.
@ast
CpG methylation regulates alle ...... s susceptibility SNP rs143383.
@en
type
label
CpG methylation regulates alle ...... s susceptibility SNP rs143383.
@ast
CpG methylation regulates alle ...... s susceptibility SNP rs143383.
@en
prefLabel
CpG methylation regulates alle ...... s susceptibility SNP rs143383.
@ast
CpG methylation regulates alle ...... s susceptibility SNP rs143383.
@en
P2093
P2860
P1433
P1476
CpG methylation regulates alle ...... is susceptibility SNP rs143383
@en
P2093
Catherine Bui
Catherine M Syddall
Louise N Reynard
P2860
P2888
P304
P356
10.1007/S00439-014-1447-Z
P577
2014-05-27T00:00:00Z
P5875
P6179
1045288214