Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome - Wikidata - awgldk - TriplyDB

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

http://www.wikidata.org/entity/Q33910479

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Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Afford New Opportunities in Inherited Cardiovascular Disease Modeling Young at Heart: Pioneering Approaches to Model Nonischaemic Cardiomyopathy with Induced Pluripotent Stem Cells G-protein Coupled Receptor Signaling in Pluripotent Stem Cell-derived Cardiovascular Cells: Implications for Disease Modeling Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges An Overview of Direct Somatic Reprogramming: The Ins and Outs of iPSCs Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discovery Cardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem Cells Bioengineering and Stem Cell Technology in the Treatment of Congenital Heart Disease Using iPS Cells toward the Understanding of Parkinson's Disease Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?RASopathies: unraveling mechanisms with animal models Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair Concise review: The magic act of generating induced pluripotent stem cells: many rabbits in the hat Current status of induced pluripotent stem cells in cardiac tissue regeneration and engineering Modelling human disease with pluripotent stem cells iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery Induced pluripotent stem cells as a disease modeling and drug screening platform The genomic stability of induced pluripotent stem cells Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes Generation of highly purified human cardiomyocytes from peripheral blood mononuclear cell-derived induced pluripotent stem cells A robust strategy for negative selection of Cre-loxP recombination-based excision of transgenes in induced pluripotent stem cells Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression A Systemized Approach to Investigate Ca(2+) Synchronization in Clusters of Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes Generation and characterization of functional cardiomyocytes derived from human T cell-derived induced pluripotent stem cells Structural and Mechanistic Insights into LEOPARD Syndrome-Associated SHP2 Mutations Molecular Basis of Gain-of-Function LEOPARD Syndrome-Associated SHP2 Mutations Clinical applications of patient-specific induced pluripotent stem cells in cardiovascular medicine.A review of Rett syndrome (RTT) with induced pluripotent stem cells Recent Advances in the Molecular Genetics of Familial Hypertrophic Cardiomyopathy in South Asian Descendants Translation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision Medicine The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and Treatment Induced pluripotent stem cell potential in medicine, specifically focused on reproductive medicine Vascular diseases await translation of blood vessels engineered from stem cells hiPSC Modeling of Inherited Cardiomyopathies Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells "Selfish spermatogonial selection": a novel mechanism for the association between advanced paternal age and neurodevelopmental disorders

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P2860

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

http://www.wikidata.org/entity/Q33910479

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

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Aaron D Kaplan

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Avinash Waghray

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Betty Chang

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Christoph Schaniel

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Eric D Adler

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Ihor R Lemischka

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Jie Su

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Klaske D Lichtenbelt

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Lei Yang

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Lisa J Edelmann

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P2860

Leopard syndrome

Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease.

Disease-specific induced pluripotent stem cells

Shp2 knockdown and Noonan/LEOPARD mutant Shp2-induced gastrulation defects

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

Acute myelomonocytic leukemia in a boy with LEOPARD syndrome (PTPN11 gene mutation positive)

PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects

How do Shp2 mutations that oppositely influence its biochemical activity result in syndromes with overlapping symptoms?

Induced pluripotent stem cells from a spinal muscular atrophy patient

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

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10.1038/NATURE09005

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7299

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465

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Marco Tartaglia

Xonia Carvajal-Vergara

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2010-06-01T00:00:00Z

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44660786

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1051785467

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20535210

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