Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease.
about
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degenerationGenomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26.Susceptibility genes for age-related maculopathy on chromosome 10q26.Analysis of Hemicentin-1, hOgg1, and E-selectin single nucleotide polymorphisms in age-related macular degenerationComplement factor H polymorphism in age-related macular degenerationGenetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degenerationCFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degenerationA variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degenerationCFH Y402H confers similar risk of soft drusen and both forms of advanced AMDGenetics of immunological and inflammatory components in age-related macular degenerationPharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.Age-related macular degeneration--emerging pathogenetic and therapeutic concepts.Age-related macular degeneration: a perspective on genetic studies.Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking.The aged retinal pigment epithelium/choroid: a potential substratum for the pathogenesis of age-related macular degeneration.Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approachIncorporating prior knowledge to facilitate discoveries in a genome-wide association study on age-related macular degeneration.Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese populationAge-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions.Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration.Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study.Smoking and age-related macular degeneration: a review of association.Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk.Genetic and functional dissection of ARMS2 in age-related macular degeneration and polypoidal choroidal vasculopathy.Further support for the common variants in complement factor H (Y402H) and LOC387715 (A69S) genes as major risk factors for the exudative age-related macular degeneration.Genetics of age-related macular degeneration: current concepts, future directions.Genome-wide association studies: getting to pathogenesis, the role of inflammation/complement in age-related macular degenerationGenetic networks in the mouse retina: growth associated protein 43 and phosphatase tensin homolog network.HTRA1 variants in exudative age-related macular degeneration and interactions with smoking and CFH.MetaNetVar: Pipeline for applying network analysis tools for genomic variants analysis.Association of Combined Complement Factor H Y402H and ARMS/LOC387715 A69S Polymorphisms with Age-related Macular Degeneration: A Meta-analysis.Genetic insights into age-related macular degeneration: controversies addressing risk, causality, and therapeutics.HEMICENTIN-1 (FIBULIN-6) and the 1q31 AMD locus in the context of complex disease: review and perspective.Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration.The role of inflammation in the pathogenesis of age-related macular degeneration.Clinical applications of whole-genome association studies: future applications at the bedside.A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degeneration.Consistently replicating locus linked to migraine on 10q22-q23An update on the genetics of age-related macular degeneration.
P2860
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P2860
Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Age-related macular degenerati ...... riched for late-stage disease.
@ast
Age-related macular degenerati ...... riched for late-stage disease.
@en
Age-related macular degenerati ...... riched for late-stage disease.
@en-gb
type
label
Age-related macular degenerati ...... riched for late-stage disease.
@ast
Age-related macular degenerati ...... riched for late-stage disease.
@en
Age-related macular degenerati ...... riched for late-stage disease.
@en-gb
prefLabel
Age-related macular degenerati ...... riched for late-stage disease.
@ast
Age-related macular degenerati ...... riched for late-stage disease.
@en
Age-related macular degenerati ...... riched for late-stage disease.
@en-gb
P2093
P2860
P50
P356
P1476
Age-related macular degenerati ...... riched for late-stage disease.
@en
P2093
Adam C Reddick
Andrew K Vine
Beverly M Yashar
Edward H Trager
Elena Filippova
John Bahling
Julia E Richards
Kari E H Branham
Mark W Johnson
Noor M Ghiasvand
P2860
P304
P356
10.1086/382786
P407
P577
2004-02-16T00:00:00Z