Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology.
about
Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescenceConditionally reprogrammed normal and transformed mouse mammary epithelial cells display a progenitor-cell-like phenotypeWild-derived inbred mouse strains have short telomeres.Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1Telomeres, telomerase, and tumorigenesis--a reviewComparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determinationCancer resistance in the blind mole rat is mediated by concerted necrotic cell death mechanismHypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-ratImmortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of BaxModels of breast cancer: quo vadis, animal modeling?New trends in molecular and cellular biomarker discovery for colorectal cancerTelomeres in aging and disease: lessons from zebrafishHuman Specific Regulation of the Telomerase Reverse Transcriptase GeneRoles and mechanisms of cellular senescence in regulation of tissue homeostasisReduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidaseRodents for comparative aging studies: from mice to beaversOxygen sensitivity severely limits the replicative lifespan of murine fibroblastsTelomere Length Maintenance and Cardio-Metabolic Disease Prevention Through Exercise Training.Characterization of chromosomal instability in murine colitis-associated colorectal cancer.Natural and pharmacological regulation of telomeraseIdentification of novel candidates for replicative senescence by functional proteomics.Differential proteome analysis of replicative senescence in rat embryo fibroblasts.Interferon-inducible IFI16, a negative regulator of cell growth, down-regulates expression of human telomerase reverse transcriptase (hTERT) gene.Correlation of telomere length shortening with promoter methylation profile of p16/Rb and p53/p21 pathways in breast cancer.A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen.Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages.Cell senescence and cancer.Role of p14(ARF) in replicative and induced senescence of human fibroblasts.Robust activation of the human but not mouse telomerase gene during the induction of pluripotency.Ecdysone and the cell cycle: investigations in a mosquito cell line.Dissociation of telomerase activity and telomere length maintenance in primitive human hematopoietic cells.Telomere biology in Metazoa.Enumeration of the simian virus 40 early region elements necessary for human cell transformationDifferential response of mature TrkA/p75(NTR) expressing human and pig oligodendrocytes: aging, does it matter?Aging, cellular senescence, and cancerDifferential cis-regulation of human versus mouse TERT gene expression in vivo: identification of a human-specific repressive element.Regulation of cellular senescence by p53.Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblastsThe La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo.
P2860
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P2860
Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology.
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Telomere dynamics in cancer pr ...... an and mouse telomere biology.
@ast
Telomere dynamics in cancer pr ...... an and mouse telomere biology.
@en
type
label
Telomere dynamics in cancer pr ...... an and mouse telomere biology.
@ast
Telomere dynamics in cancer pr ...... an and mouse telomere biology.
@en
prefLabel
Telomere dynamics in cancer pr ...... an and mouse telomere biology.
@ast
Telomere dynamics in cancer pr ...... an and mouse telomere biology.
@en
P356
P1433
P1476
Telomere dynamics in cancer pr ...... an and mouse telomere biology.
@en
P2093
P2888
P304
P356
10.1038/78592
P407
P577
2000-08-01T00:00:00Z
P6179
1032345919