Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1.

Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1.

Item
http://www.wikidata.org/entity/Q33914011
Integrins in the Spotlight of CancerMolecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis.IGF-IR promotes prostate cancer growth by stabilizing α5β1 integrin protein levelsβ1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progenyFrequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.Osteoblast-secreted collagen upregulates paracrine Sonic hedgehog signaling by prostate cancer cells and enhances osteoblast differentiation.β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse modelβ4 Integrin signaling induces expansion of prostate tumor progenitorsGalectin-1 from cancer-associated fibroblasts induces epithelial-mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancer.RGD-Binding Integrins in Prostate Cancer: Expression Patterns and Therapeutic Prospects against Bone Metastasis.Essential function for PDLIM2 in cell polarization in three-dimensional cultures by feedback regulation of the β1-integrin-RhoA signaling axis.β1 integrins mediate resistance to ionizing radiation in vivo by inhibiting c-Jun amino terminal kinase 1.Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cellsβ1 integrin: an emerging player in the modulation of tumorigenesis and response to therapy.PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer.Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts.
P2860

Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1.

Item
http://www.wikidata.org/entity/Q33914011
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Beta1 integrins mediate cell p ...... dgehog effector protein, GLI1.
@ast
Beta1 integrins mediate cell p ...... dgehog effector protein, GLI1.
@en
type
label
Beta1 integrins mediate cell p ...... dgehog effector protein, GLI1.
@ast
Beta1 integrins mediate cell p ...... dgehog effector protein, GLI1.
@en
prefLabel
Beta1 integrins mediate cell p ...... dgehog effector protein, GLI1.
@ast
Beta1 integrins mediate cell p ...... dgehog effector protein, GLI1.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932
P356
P1433
P1476
Beta1 integrins mediate cell p ...... dgehog effector protein, GLI1.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932