Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
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Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis.Elevated Slit2 Activity Impairs VEGF-Induced Angiogenesis and Tumor Neovascularization in EphA2-Deficient EndotheliumSlit2 overexpression results in increased microvessel density and lesion size in mice with induced endometriosis.Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathwayAngiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.The role of SLIT-ROBO signaling in proliferative diabetic retinopathy and retinal pigment epithelial cellsSLIT/ROBO1 signaling suppresses mammary branching morphogenesis by limiting basal cell numberSlit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesisSlit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway.A potential small-molecule synthetic antilymphangiogenic agent norcantharidin inhibits tumor growth and lymphangiogenesis of human colonic adenocarcinomas through blocking VEGF-A,-C,-D/VEGFR-2,-3 "multi-points priming" mechanisms in vitro and in vivGenetic predictors of susceptibility to cutaneous fungal infections: a pilot genome wide association study to refine a candidate gene search.Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularizationSlit2‑Robo1 signaling promotes the adhesion, invasion and migration of tongue carcinoma cells via upregulating matrix metalloproteinases 2 and 9, and downregulating E‑cadherin.Over-expression of Slit2 induces vessel formation and changes blood vessel permeability in mouse brain.Slit2 suppresses endothelial cell proliferation and migration by inhibiting the VEGF-Notch signaling pathway.A roundabout way to cancer.Immunohistochemical staining of slit2 in primary and metastatic prostatic adenocarcinoma.The lymphatic system and pancreatic cancer.Slit2 promotes tumor growth and invasion in chemically induced skin carcinogenesis.A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer.Differential gene expression profiling of matched primary renal cell carcinoma and metastases reveals upregulation of extracellular matrix genes.The Role of Circulating Slit2, the One of the Newly Batokines, in Human Diabetes Mellitus.Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity.Deregulated angiogenesis in chronic lung diseases: a possible role for lung mesenchymal progenitor cells (2017 Grover Conference Series).The differential roles of Slit2-exon 15 splicing variants in angiogenesis and HUVEC permeability.Inhibition of endothelial Slit2/Robo1 signaling by thalidomide restrains angiogenesis by blocking the PI3K/Akt pathway.
P2860
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P2860
Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
@en
type
label
Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
@en
prefLabel
Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
@en
P2093
P2860
P1476
Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
@en
P2093
Hai-Xiong Han
Jian-Guo Geng
Xiao-Mei Yang
Yu-Min Dai
P2860
P304
P356
10.1016/J.BBRC.2010.04.152
P407
P577
2010-05-08T00:00:00Z