Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome. - Wikidata - awgldk - TriplyDB

Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome.

Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome.

http://www.wikidata.org/entity/Q33919627

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The PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.Recent advances in understanding synaptic abnormalities in Rett syndrome Developmental Dynamics of Rett Syndrome Characterizing autism spectrum disorders by key biochemical pathways.Genes, circuits, and precision therapies for autism and related neurodevelopmental disorders MECP2 disorders: from the clinic to mice and back Dendritic spine dysgenesis in autism related disorders Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes MeCP2 Affects Skeletal Muscle Growth and Morphology through Non Cell-Autonomous Mechanisms Illness Severity, Social and Cognitive Ability, and EEG Analysis of Ten Patients with Rett Syndrome Treated with Mecasermin (Recombinant Human IGF-1).Rett Syndrome: Reaching for Clinical Trials Insulin-Like Growth Factor 1 and Related Compounds in the Treatment of Childhood-Onset Neurodevelopmental Disorders Advancing the understanding of autism disease mechanisms through genetics Rett syndrome: disruption of epigenetic control of postnatal neurological functions Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression Characterization of Rett Syndrome-like phenotypes in Mecp2-knockout rats Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome.mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment.β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome Insulin-like Growth Factor 1 for Healthy Spines and Healthy Minds?Dendritic spine dysgenesis in Rett syndrome.Regulation of IGF -1 signaling by microRNAs.Rett syndrome like phenotypes in the R255X Mecp2 mutant mouse are rescued by MECP2 transgene Cognition and mood-related behaviors in L3mbtl1 null mutant mice.MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.Anxiety-like behavior in Rett syndrome: characteristics and assessment by anxiety scales.KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice.Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice.MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome.The therapeutic potential of insulin-like growth factor-1 in central nervous system disorders.Concise Review: Progress and Challenges in Using Human Stem Cells for Biological and Therapeutics Discovery: Neuropsychiatric Disorders.Enhancement of postsynaptic GABAA and extrasynaptic NMDA receptor-mediated responses in the barrel cortex of Mecp2-null mice.Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome.Jointly reduced inhibition and excitation underlies circuit-wide changes in cortical processing in Rett syndrome.Neurobiologically-based treatments in Rett syndrome: opportunities and challenges.Insulin-Like Growth Factor 1: At the Crossroads of Brain Development and Aging.Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?

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Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome.

http://www.wikidata.org/entity/Q33919627

description

2014 nî lūn-bûn

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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Functional recovery with recom ...... mouse model of Rett Syndrome.

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Functional recovery with recom ...... mouse model of Rett Syndrome.

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PNAS.1311685111

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Proceedings of the National Academy of Sciences of the United States of America

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Functional recovery with recom ...... mouse model of Rett Syndrome.

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P2093

Abhishek Banerjee

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Jonathan Woodson

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Jorge Castro

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Mriganka Sur

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Nikolaos Mellios

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Rodrigo I Garcia

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Showming Kwok

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P2860

MeCP2, a key contributor to neurological disease, activates and represses transcription

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

The story of Rett syndrome: from clinic to neurobiology

SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number

Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice

Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons

Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome

A critical and cell-autonomous role for MeCP2 in synaptic scaling up

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10.1073/PNAS.1311685111

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27

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111

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Jeremy Petravicz

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2014-06-23T00:00:00Z

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263397492

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24958891

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4103342

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