Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. - Wikidata - awgldk - TriplyDB

Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting.

Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting.

http://www.wikidata.org/entity/Q33922759

about

Ezrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3 Ezrin induces long-range interdomain allostery in the scaffolding protein NHERF1 Open conformation of ezrin bound to phosphatidylinositol 4,5-bisphosphate and to F-actin revealed by neutron scattering Spatiotemporal patterning during T cell activation is highly diverse.Modulation of angiotensin II-induced inflammatory cytokines by the Epac1-Rap1A-NHE3 pathway: implications in renal tubular pathobiology.Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling.Luminal Na(+)/H (+) exchange in the proximal tubule Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cells.Unique regulation of human Na+/H+ exchanger 3 (NHE3) by Nedd4-2 ligase that differs from non-primate NHE3s.NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid.The NHE3 juxtamembrane cytoplasmic domain directly binds ezrin: dual role in NHE3 trafficking and mobility in the brush border.Elevated calcium acutely regulates dynamic interactions of NHERF2 and NHE3 proteins in opossum kidney (OK) cell microvilli.The Na+/H+ Exchanger-3 (NHE3) Activity Requires Ezrin Binding to Phosphoinositide and Its Phosphorylation.Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3.The epithelial sodium/proton exchanger, NHE3, is necessary for renal and intestinal calcium (re)absorption Emerging roles of alkali cation/proton exchangers in organellar homeostasis.The regulation of proximal tubular salt transport in hypertension: an update.Carbonic anhydrase II binds to and increases the activity of the epithelial sodium-proton exchanger, NHE3 The calcineurin homologous protein-1 increases Na(+)/H(+) -exchanger 3 trafficking via ezrin phosphorylation Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response.Red fluorescent protein pH biosensor to detect concentrative nucleoside transport Mechanisms of the regulation of the intestinal Na+/H+ exchanger NHE3 BetaPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction.Analysis of detergent-free lipid rafts isolated from CD4+ T cell line: interaction with antigen presenting cells promotes coalescing of lipid rafts.Functional analysis of human RhCG: comparison with E. coli ammonium transporter reveals similarities in the pore and differences in the vestibule.RhoA required for acid-induced stress fiber formation and trafficking and activation of NHE3.Membrane curvature alters the activation kinetics of the epithelial Na+/H+ exchanger, NHE3.High-mobility group box 1 inhibits HCO3- absorption in the medullary thick ascending limb through RAGE-Rho-ROCK-mediated inhibition of basolateral Na+/H+ exchange.Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger.Differential association of the Na+/H+ Exchanger Regulatory Factor (NHERF) family of adaptor proteins with the raft- and the non-raft brush border membrane fractions of NHE3.Loss of PDZ-adaptor protein NHERF2 affects membrane localization and cGMP- and [Ca2+]- but not cAMP-dependent regulation of Na+/H+ exchanger 3 in murine intestine.Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.EGF increases TRPM6 activity and surface expression.Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling.Identification and biochemical characterization of the SLC9A7 interactome.

P2860

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P2860

Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting.

http://www.wikidata.org/entity/Q33922759

description

2005 nî lūn-bûn

@nan

2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Rho GTPases dictate the mobili ...... pical retention and targeting.

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Rho GTPases dictate the mobili ...... pical retention and targeting.

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type

label

Rho GTPases dictate the mobili ...... pical retention and targeting.

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Rho GTPases dictate the mobili ...... pical retention and targeting.

@en

prefLabel

Rho GTPases dictate the mobili ...... pical retention and targeting.

@ast

Rho GTPases dictate the mobili ...... pical retention and targeting.

@en

P1433

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PNAS.0409197102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Rho GTPases dictate the mobili ...... pical retention and targeting.

@en

P2093

John Orlowski

http://www.w3.org/2001/XMLSchema#string

Katalin Szászi

http://www.w3.org/2001/XMLSchema#string

R Todd Alexander

http://www.w3.org/2001/XMLSchema#string

Wendy Furuya

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family

The Na+/H+ exchanger NHE-1 possesses N- and O-linked glycosylation restricted to the first N-terminal extracellular domain

Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3

Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor

Specific association of megalin and the Na+/H+ exchanger isoform NHE3 in the proximal tubule.

Active (9.6 s) and inactive (21 s) oligomers of NHE3 in microdomains of the renal brush border.

The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP.

Intracellular pH.

Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro

Structure and function of the NHE1 isoform of the Na+/H+ exchanger.

P304

12253-12258

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P31

scholarly article

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10.1073/PNAS.0409197102

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P407

P433

34

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P478

102

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P50

Sergio Grinstein

P577

2005-08-15T00:00:00Z

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P5875

7658012

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P698

16103375

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P932

1189301

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