Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells. - Wikidata - awgldk - TriplyDB

Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells.

Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells.

http://www.wikidata.org/entity/Q33922779

about

Reflections on early malaria vaccine studies, the first successful human malaria vaccination, and beyond Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa Acquired immunity to malaria Ambivalent Outcomes of Cell Apoptosis: A Barrier or Blessing in Malaria Progression Selection and refinement: the malaria parasite's infection and exploitation of host hepatocytes Structural and biochemical characterization of Plasmodium falciparum 12 (Pf12) reveals a unique interdomain organization and the potential for an antiparallel arrangement with Pf41 CD8(+) T cells mediate robust stage-specific immunity to P. berghei under chemoprophylaxis and this protective environment is not downregulated by the presence of blood-stage infection Structure of the Plasmodium 6-cysteine s48/45 domain Proteins of the malaria parasite sexual stages: expression, function and potential for transmission blocking strategies A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase Systematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparum Biochemical and functional analysis of two Plasmodium falciparum blood-stage 6-cys proteins: P12 and P41 A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites Plasmodium berghei histamine-releasing factor favours liver-stage development via inhibition of IL-6 production and associates with a severe outcome of disease Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design Inactivation of a Plasmodium apicoplast protein attenuates formation of liver merozoites Malaria parasites target the hepatocyte receptor EphA2 for successful host infection Plasmodium yoelii sporozoites modulate cytokine profile and induce apoptosis in murine Kupffer cells.Imaging Plasmodium immunobiology in the liver, brain, and lung.A rapid and robust selection procedure for generating drug-selectable marker-free recombinant malaria parasites.Serial Analysis of Gene Expression in Plasmodium berghei salivary gland sporozoites.Sterile protection against malaria is independent of immune responses to the circumsporozoite protein.Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection.Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes.Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) Plasmodium sporozoites Immunization with radiation-attenuated Plasmodium berghei sporozoites induces liver cCD8alpha+DC that activate CD8+T cells against liver-stage malaria.A role for immune responses against non-CS components in the cross-species protection induced by immunization with irradiated malaria sporozoites.Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria.Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model.Role of Plasmodium berghei cGMP-dependent protein kinase in late liver stage development Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts.Malaria parasite development in the mosquito and infection of the mammalian host.Engineering of Genetically Arrested Parasites (GAPs) For a Precision Malaria Vaccine Plasmodium P36 determines host cell receptor usage during sporozoite invasion Minimal role for the circumsporozoite protein in the induction of sterile immunity by vaccination with live rodent malaria sporozoites Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

P2860

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P2860

Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells.

http://www.wikidata.org/entity/Q33922779

description

2005 nî lūn-bûn

@nan

2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի օգոստոսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Genetically attenuated, P36p-d ...... tosis of infected liver cells.

@ast

Genetically attenuated, P36p-d ...... tosis of infected liver cells.

@en

type

label

Genetically attenuated, P36p-d ...... tosis of infected liver cells.

@ast

Genetically attenuated, P36p-d ...... tosis of infected liver cells.

@en

prefLabel

Genetically attenuated, P36p-d ...... tosis of infected liver cells.

@ast

Genetically attenuated, P36p-d ...... tosis of infected liver cells.

@en

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P356

PNAS.0500925102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Genetically attenuated, P36p-d ...... tosis of infected liver cells.

@en

P2093

Andrew P Waters

http://www.w3.org/2001/XMLSchema#string

Ben van Schaijk

http://www.w3.org/2001/XMLSchema#string

Maaike W van Dooren

http://www.w3.org/2001/XMLSchema#string

Melissa R van Dijk

http://www.w3.org/2001/XMLSchema#string

Volker Heussler

http://www.w3.org/2001/XMLSchema#string

P2860

Gliding motility and cell invasion by Apicomplexa: insights from the Plasmodium sporozoite

Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity

Discovery of gene function by expression profiling of the malaria parasite life cycle

A malaria membrane skeletal protein is essential for normal morphogenesis, motility, and infectivity of sporozoites

A central role for P48/45 in malaria parasite male gamete fertility

TRAP is necessary for gliding motility and infectivity of plasmodium sporozoites

Exploring the transcriptome of the malaria sporozoite stage

Migration of Plasmodium sporozoites through cells before infection.

Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface

IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model.

P304

12194-12199

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scholarly article

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10.1073/PNAS.0500925102

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P407

P433

34

http://www.w3.org/2001/XMLSchema#string

P478

102

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P50

Geert-Jan van Gemert

Blandine Franke-Fayard

Bruno Douradinha

Robert W Sauerwein

Maria Manuel Dias da Mota

P577

2005-08-15T00:00:00Z

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P5875

7657994

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P698

16103357

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P921

6-cysteine protein P52

6-cysteine protein P52, putative

6-cysteine protein P52

P932

1189305

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