Development of a novel high-throughput screen and identification of small-molecule inhibitors of the Gα-RGS17 protein-protein interaction using AlphaScreen.
about
A high throughput screen for RGS proteins using steady state monitoring of free phosphate formationThe evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell LinesRGS17: an emerging therapeutic target for lung and prostate cancers.Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolaeRegulator of G Protein Signaling 17 as a Negative Modulator of GPCR Signaling in Multiple Human Cancers.Increasing the range of drug targets: interacting peptides provide leads for the development of oncoprotein inhibitors.Development of a bimolecular luminescence complementation assay for RGS: G protein interactions in cells.Current Experimental Methods for Characterizing Protein-Protein Interactions.The Gαi-GIV binding interface is a druggable protein-protein interaction
P2860
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P2860
Development of a novel high-throughput screen and identification of small-molecule inhibitors of the Gα-RGS17 protein-protein interaction using AlphaScreen.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Development of a novel high-th ...... interaction using AlphaScreen.
@ast
Development of a novel high-th ...... interaction using AlphaScreen.
@en
type
label
Development of a novel high-th ...... interaction using AlphaScreen.
@ast
Development of a novel high-th ...... interaction using AlphaScreen.
@en
prefLabel
Development of a novel high-th ...... interaction using AlphaScreen.
@ast
Development of a novel high-th ...... interaction using AlphaScreen.
@en
P2860
P356
P1476
Development of a novel high-th ...... interaction using AlphaScreen.
@en
P2093
David L Roman
Duncan I Mackie
P2860
P304
P356
10.1177/1087057111410427
P577
2011-06-16T00:00:00Z