Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways.
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Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex.Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liverViruses associated with human cancerHepatitis B virus X protein and simian virus 5 V protein exhibit similar UV-DDB1 binding properties to mediate distinct activitiesX region mutations of hepatitis B virus related to clinical severityHypoxia-inducible factors as molecular targets for liver diseasesHepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseasesHarnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinomaHepatocellular carcinoma: Epidemiology, risk factors and pathogenesisHepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2Hepatitis B virus molecular biology and pathogenesisCytochrome C oxidase III interacts with hepatitis B virus X protein in vivo by yeast two-hybrid system.Hepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death.Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo.Hepatocellular carcinoma and the underlying mechanisms.Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor.The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage.Effects of NFKB1 and NFKBIA gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathological features.HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascadeChronic hepatitis B infection and liver cancer.Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro.Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles.Effects of CpG-ODNs on phenotype and function of monocyte-derived dendritic cells in chronic hepatitis B.Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level.Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinoma.Aggregate formation of hepatitis B virus X protein affects cell cycle and apoptosis.Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance.The molecular diagnosis of hepatitis B virus-associated hepatocellular carcinoma.HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma.Hepatitis viruses: live and let die.Differential expression of hepatic apurinic/apyrimidinic endonuclease 1, a DNA repair enzyme, in chronic hepatitis.Hepatitis B virus X protein modulates apoptosis in human renal proximal tubular epithelial cells by activating the JAK2/STAT3 signaling pathway.Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes.Specific mutations of hepatitis B virus in plasma predict liver cancer development.Inactivation of hepatitis B virus replication in cultured cells and in vivo with engineered transcription activator-like effector nucleases.Efficient silencing of gene expression with modular trimeric Pol II expression cassettes comprising microRNA shuttles.HBx Gene Mutations in Hepatitis B Virus and Hepatocellular Carcinoma.Hepatitis B Virus Protein X Induces Degradation of Talin-1.iTRAQ-Based Proteomics Identification of Serum Biomarkers of Two Chronic Hepatitis B Subtypes Diagnosed by Traditional Chinese Medicine.Hepatitis B virus X protein in liver tumor microenvironment.
P2860
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P2860
Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways.
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
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2000年學術文章
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name
Putative role of hepatitis B v ...... kinase and JAK/STAT pathways.
@ast
Putative role of hepatitis B v ...... kinase and JAK/STAT pathways.
@en
type
label
Putative role of hepatitis B v ...... kinase and JAK/STAT pathways.
@ast
Putative role of hepatitis B v ...... kinase and JAK/STAT pathways.
@en
prefLabel
Putative role of hepatitis B v ...... kinase and JAK/STAT pathways.
@ast
Putative role of hepatitis B v ...... kinase and JAK/STAT pathways.
@en
P2093
P2860
P1476
Putative role of hepatitis B v ...... kinase and JAK/STAT pathways.
@en
P2093
P2860
P304
P356
10.1046/J.1440-1746.2000.02069.X
P577
2000-04-01T00:00:00Z