Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity.
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Recent advances in coeliac diseaseRole of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprueIn vivo fluorescence imaging of exogenous enzyme activity in the gastrointestinal tractCrystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factorProtein engineering of improved prolyl endopeptidases for celiac sprue therapyDipeptidyl Aminopeptidase IV from Stenotrophomonas maltophilia Exhibits Activity against a Substrate Containing a 4-Hydroxyproline ResidueInduced-fit mechanism for prolyl endopeptidase.Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASEMolecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase.A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATIONCrystal structures of Trypanosoma brucei oligopeptidase B broaden the paradigm of catalytic regulation in prolyl oligopeptidase family enzymesCatalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionalityStructure and Mechanism of the Sphingopyxin I Lasso Peptide IsopeptidaseStructural analysis of prolyl oligopeptidases using molecular docking and dynamics: insights into conformational changes and ligand bindingMolecular dynamics study of prolyl oligopeptidase with inhibitor in binding cavity.Peptidomics of prolyl endopeptidase in the central nervous system.Mechanisms of intramolecular communication in a hyperthermophilic acylaminoacyl peptidase: a molecular dynamics investigation.Proline-Glycine-Proline (PGP) and High Mobility Group Box Protein-1 (HMGB1): Potential Mediators of Cystic Fibrosis Airway Inflammation.Permeation through phospholipid bilayers, skin-cell penetration, plasma stability, and CD spectra of α- and β-oligoproline derivatives.Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown.Distribution, classification, domain architectures and evolution of prolyl oligopeptidases in prokaryotic lineages.Enzyme Tunnels and Gates As Relevant Targets in Drug Design.The expanding diversity of serine hydrolasesCharacterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants.Parasite prolyl oligopeptidases and the challenge of designing chemotherapeuticals for Chagas disease, leishmaniasis and African trypanosomiasisProcessing of the phalloidin proprotein by prolyl oligopeptidase from the mushroom Conocybe albipesA typhus group-specific protease defies reductive evolution in rickettsiae.A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammationTargeted modification of wheat grain protein to reduce the content of celiac causing epitopes.The matrikine PGP as a potential biomarker in COPD.Prolyl-specific peptidases for applications in food protein hydrolysis.Mycobacterium tuberculosis Prolyl Oligopeptidase Induces In vitro Secretion of Proinflammatory Cytokines by Peritoneal Macrophages.Physiopathology and Management of Gluten-Induced Celiac Disease.Gene cloning and enzymatic characterization of an endoprotease Endo-Pro-Aspergillus niger.Computational Analysis of the Domain Architecture and Substrate-Gating Mechanism of Prolyl Oligopeptidases from Shewanella woodyi and Identification of Probable Lead Molecules.Computational analysis of the domain architecture and substrate-gating mechanism of prolyl oligopeptidases from Shewanella woodyi and identification probable lead molecules.Expression, purification, crystallization and preliminary X-ray diffraction analysis of acylpeptide hydrolase from Deinococcus radiodurans.Oral enzyme therapy for celiac sprue.Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry
P2860
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P2860
Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structural and mechanistic ana ...... in catalysis and specificity.
@ast
Structural and mechanistic ana ...... in catalysis and specificity.
@en
type
label
Structural and mechanistic ana ...... in catalysis and specificity.
@ast
Structural and mechanistic ana ...... in catalysis and specificity.
@en
prefLabel
Structural and mechanistic ana ...... in catalysis and specificity.
@ast
Structural and mechanistic ana ...... in catalysis and specificity.
@en
P2860
P356
P1476
Structural and mechanistic ana ...... s in catalysis and specificity
@en
P2093
Chaitan Khosla
Irimpan I Mathews
P2860
P304
P356
10.1073/PNAS.0408286102
P407
P50
P577
2005-02-28T00:00:00Z