Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy.
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Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stressCorrection of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapyDoes use of isotretinoin rule out a career in flying?Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6Photoreceptor cell death and rescue in retinal detachment and degenerationsRetina, retinol, retinal and the natural history of vitamin A as a light sensorAlpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activityPBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced DamageEvidence that light modulates protein nitration in rat retina.Rpe65 as a modifier gene for inherited retinal degenerationAccelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementationPositively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycleEffects of organic solvents on two retinal pigment epithelial lipofuscin fluorophores, A2E and all-trans-retinal dimerEffects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice.Pharmacological inhibition of lipofuscin accumulation in the retina as a therapeutic strategy for dry AMD treatment.Microsomal glutathione S-transferase 1 in the retinal pigment epithelium: protection against oxidative stress and a potential role in aging.Exome analysis identified a novel mutation in the RBP4 gene in a consanguineous pedigree with retinal dystrophy and developmental abnormalities.Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.Therapy for macular degeneration: insights from acneTreatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration.Redox proteomic identification of visual arrestin dimerization in photoreceptor degeneration after photic injury.The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration.Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies.Molecular pharmacodynamics of emixustat in protection against retinal degeneration.Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front.Retinal photodamage mediated by all-trans-retinal.Light-induced damage to the retina: role of rhodopsin chromophore revisited.Light and inherited retinal degeneration.Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agentsProlonged Inner Retinal Photoreception Depends on the Visual Retinoid Cycle.Retinal pigment epithelium lipofuscin proteomics.Inhibition of de novo ceramide biosynthesis by FTY720 protects rat retina from light-induced degeneration.Characterization of dihydro-A2PE: an intermediate in the A2E biosynthetic pathway.Reduced-illuminance autofluorescence imaging in ABCA4-associated retinal degenerations.Loss of retinoschisin (RS1) cell surface protein in maturing mouse rod photoreceptors elevates the luminance threshold for light-driven translocation of transducin but not arrestin.Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt diseaseRpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E.Cleavage of the retinal pigment epithelium-specific protein RPE65 under oxidative stress.The membrane receptor for plasma retinol-binding protein, a new type of cell-surface receptor.Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration.
P2860
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P2860
Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Inhibition of the visual cycle ...... dness in isotretinoin therapy.
@ast
Inhibition of the visual cycle ...... dness in isotretinoin therapy.
@en
type
label
Inhibition of the visual cycle ...... dness in isotretinoin therapy.
@ast
Inhibition of the visual cycle ...... dness in isotretinoin therapy.
@en
prefLabel
Inhibition of the visual cycle ...... dness in isotretinoin therapy.
@ast
Inhibition of the visual cycle ...... dness in isotretinoin therapy.
@en
P2093
P2860
P356
P1476
Inhibition of the visual cycle ...... ndness in isotretinoin therapy
@en
P2093
D A Thompson
M Provenzano
P A Sieving
P Chaudhry
T J Carlson
P2860
P304
P356
10.1073/PNAS.041606498
P407
P50
P577
2001-02-06T00:00:00Z