Signaling properties of a covalent modification cycle are altered by a downstream target.
about
Control theory meets synthetic biologyRetroactivity in the Context of Modularly Structured Biomolecular SystemsRetroactive signaling in short signaling pathwaysLoads bias genetic and signaling switches in synthetic and natural systemsExploiting the dynamic properties of covalent modification cycle for the design of synthetic analog biomolecular circuitryUltrasensitive response motifs: basic amplifiers in molecular signalling networks.Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspectiveTuning genetic clocks employing DNA binding sites.Reciprocal regulation as a source of ultrasensitivity in two-component systems with a bifunctional sensor kinase.Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity.Multi-target regulation by small RNAs synchronizes gene expression thresholds and may enhance ultrasensitive behavior.Substrate-dependent control of ERK phosphorylation can lead to oscillationsEngineering and ethical perspectives in synthetic biology. Rigorous, robust and predictable designs, public engagement and a modern ethical framework are vital to the continued success of synthetic biology.Signaling cascades transmit information downstream and upstream but unlikely simultaneously.The energy costs of insulators in biochemical networksModulation of CYP19 expression by cabbage juices and their active components: indole-3-carbinol and 3,3'-diindolylmethene in human breast epithelial cell lines.Interactions Between phyB and PIF Proteins Alter Thermal Reversion Reactions in vitro.Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations.Unraveling the complex regulatory relationships between metabolism and signal transduction in cancer.Core signalling motif displaying multistability through multi-state enzymes.Sensitivity and robustness in covalent modification cycles with a bifunctional converter enzyme.The robustness of the Escherichia coli signal-transducing UTase/UR-PII covalent modification cycle to variation in the PII concentration requires very strong inhibition of the UTase activity of UTase/UR by glutamine.A load driver device for engineering modularity in biological networks.Long signaling cascades tend to attenuate retroactivity.Mathematical study of the role of Delta/Notch lateral inhibition during primary branching of Drosophila trachea development.Substrate-dependent control of MAPK phosphorylation in vivoIntrinsic feedbacks in MAPK signaling cascades lead to bistability and oscillations.Push-Pull and Feedback Mechanisms Can Align Signaling System Outputs with Inputs.Signaling Architectures that Transmit Unidirectional Information Despite Retroactivity.A Discrete Dynamical System Approach to Pathway Activation Profiles of Signaling Cascades.GlnK Facilitates the Dynamic Regulation of Bacterial Nitrogen Assimilation.Invariants reveal multiple forms of robustness in bifunctional enzyme systems.Load-induced modulation of signal transduction networks.
P2860
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P2860
Signaling properties of a covalent modification cycle are altered by a downstream target.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Signaling properties of a covalent modification cycle are altered by a downstream target.
@ast
Signaling properties of a covalent modification cycle are altered by a downstream target.
@en
type
label
Signaling properties of a covalent modification cycle are altered by a downstream target.
@ast
Signaling properties of a covalent modification cycle are altered by a downstream target.
@en
prefLabel
Signaling properties of a covalent modification cycle are altered by a downstream target.
@ast
Signaling properties of a covalent modification cycle are altered by a downstream target.
@en
P2093
P2860
P356
P1476
Signaling properties of a covalent modification cycle are altered by a downstream target.
@en
P2093
Alejandra C Ventura
Alexander J Ninfa
Domitilla Del Vecchio
Lauren Van Wassenhove
Peng Jiang
Sofia D Merajver
P2860
P304
10032-10037
P356
10.1073/PNAS.0913815107
P407
P577
2010-05-17T00:00:00Z