Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion. - Wikidata - awgldk - TriplyDB

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion.

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion.

http://www.wikidata.org/entity/Q33934074

about

Furin at the cutting edge: from protein traffic to embryogenesis and disease Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses Use of a novel cell-based fusion reporter assay to explore the host range of human respiratory syncytial virus F protein.Unity in diversity: shared mechanism of entry among paramyxoviruses Host cell entry of respiratory syncytial virus involves macropinocytosis followed by proteolytic activation of the F protein Furin Processing and Proteolytic Activation of Semliki Forest Virus Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers Principles of Virus Uncoating: Cues and the Snooker Ball Analysis of Human RSV Immunity at the Molecular Level: Learning from the Past and Present Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy.High level expression of soluble glycoproteins in the allantoic fluid of embryonated chicken eggs using a Sendai virus minigenome system Animal pneumoviruses: molecular genetics and pathogenesis.Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein.Structure and function of respiratory syncytial virus surface glycoproteins.Identification of immunodominant epitopes derived from the respiratory syncytial virus fusion protein that are recognized by human CD4 T cells.A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles.Inhibition of respiratory syncytial virus fusion by the small molecule VP-14637 via specific interactions with F protein.Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis.Soluble respiratory syncytial virus fusion protein in the fully cleaved, pretriggered state is triggered by exposure to low-molarity buffer.Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry.Emerging paramyxoviruses: molecular mechanisms and antiviral strategies Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics.Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein Cholesterol-rich microdomains as docking platforms for respiratory syncytial virus in normal human bronchial epithelial cells Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis Respiratory syncytial virus, an ongoing medical dilemma: an expert commentary on respiratory syncytial virus prophylactic and therapeutic pharmaceuticals currently in clinical trials Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention.In search of a small-molecule inhibitor for respiratory syncytial virus.Paramyxovirus fusion and entry: multiple paths to a common end Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.Trypsin- and low pH-mediated fusogenicity of avian metapneumovirus fusion proteins is determined by residues at positions 100, 101 and 294.New generation live vaccines against human respiratory syncytial virus designed by reverse genetics.Characterization of EBV gB indicates properties of both class I and class II viral fusion proteins.Viral and host factors in human respiratory syncytial virus pathogenesis.Generation and characterization of non-competitive furin-inhibiting nanobodies.Respiratory syncytial virus: virology, reverse genetics, and pathogenesis of disease.The comparative genomics of human respiratory syncytial virus subgroups A and B: genetic variability and molecular evolutionary dynamics.Low-pH triggering of human metapneumovirus fusion: essential residues and importance in entry.Influence of Respiratory Syncytial Virus F Glycoprotein Conformation on Induction of Protective Immune Responses.

P2860

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P2860

Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion.

http://www.wikidata.org/entity/Q33934074

description

2001 nî lūn-bûn

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2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2001 թվականի օգոստոսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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Cleavage of the human respirat ...... activation of membrane fusion.

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Cleavage of the human respirat ...... activation of membrane fusion.

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Cleavage of the human respirat ...... activation of membrane fusion.

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Cleavage of the human respirat ...... activation of membrane fusion.

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Cleavage of the human respirat ...... activation of membrane fusion.

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Cleavage of the human respirat ...... activation of membrane fusion.

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Proceedings of the National Academy of Sciences of the United States of America

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Cleavage of the human respirat ...... activation of membrane fusion.

@en

P2093

B García-Barreno

http://www.w3.org/2001/XMLSchema#string

D C Wiley

http://www.w3.org/2001/XMLSchema#string

J A López

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J A Melero

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J J Skehel

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J P Albar

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L Calder

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L González-Reyes

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M B Ruiz-Argüello

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P2860

Structural basis for paramyxovirus-mediated membrane fusion

Structural characterization of the human respiratory syncytial virus fusion protein core

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin

Role of hemagglutinin cleavage for the pathogenicity of influenza virus.

Paramyxovirus fusion (F) protein: a conformational change on cleavage activation.

Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for va

Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant.

Priming with a secreted form of the fusion protein of respiratory syncytial virus (RSV) promotes interleukin-4 (IL-4) and IL-5 production but not pulmonary eosinophilia following RSV challenge

Nucleotide sequence of the G protein gene of human respiratory syncytial virus reveals an unusual type of viral membrane protein.

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9859-9864

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10.1073/PNAS.151098198

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17

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98

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2001-08-07T00:00:00Z

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11850396

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11493675

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membrane fusion involved in viral entry into host cell

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55543

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