Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors
about
Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotypeDouble-stranded linear duck hepatitis B virus (DHBV) stably integrates at a higher frequency than wild-type DHBV in LMH chicken hepatoma cells.Clonal expansion of hepatocytes during chronic woodchuck hepatitis virus infection.In vivo effects of mutations in woodchuck hepatitis virus enhancer II.p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomasHepatitis B and C virus hepatocarcinogenesis: lessons learned and future challenges.pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutantsA new hepadnavirus endemic in arctic ground squirrels in Alaska.Woodchuck hepatitis virus X protein is present in chronically infected woodchuck liver and woodchuck hepatocellular carcinomas which are permissive for viral replication.Analysis of integrated ground squirrel hepatitis virus and flanking host DNA in two hepatocellular carcinomas.Expression of the woodchuck N-myc2 retroposon in brain and in liver tumors is driven by a cryptic N-myc promoter.Evidence for long-range oncogene activation by hepadnavirus insertionDetection of clonally expanded hepatocytes in chimpanzees with chronic hepatitis B virus infection.Cellular factors controlling the activity of woodchuck hepatitis virus enhancer II.Liver cell transformation in chronic HBV infection.HBV DNA Integration: Molecular Mechanisms and Clinical ImplicationsAntisense downregulation of N-myc1 in woodchuck hepatoma cells reverses the malignant phenotype.Woodchuck hepatitis virus enhancer I and enhancer II are both involved in N-myc2 activation in woodchuck liver tumors.Structure and glycosylation patterns of surface proteins from woodchuck hepatitis virus.Functional analysis of ground squirrel hepatitis virus enhancer II.Apoptosis is induced by N-myc expression in hepatocytes, a frequent event in hepadnavirus oncogenesis, and is blocked by insulin-like growth factor II.The HNF1/HNF4-dependent We2 element of woodchuck hepatitis virus controls viral replication and can activate the N-myc2 promoter.Increase in the frequency of hepadnavirus DNA integrations by oxidative DNA damage and inhibition of DNA repair.Differential activation of myc gene family members in hepatic carcinogenesis by closely related hepatitis B viruses.Hepatocellular carcinomaHost functions used by hepatitis B virus to complete its life cycle: Implications for developing host-targeting agents to treat chronic hepatitis B
P2860
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P2860
Hepadnavirus integration: mechanisms of activation of the N-myc2 retrotransposon in woodchuck liver tumors
description
1992 nî lūn-bûn
@nan
1992 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Hepadnavirus integration: mech ...... oson in woodchuck liver tumors
@ast
Hepadnavirus integration: mech ...... oson in woodchuck liver tumors
@en
type
label
Hepadnavirus integration: mech ...... oson in woodchuck liver tumors
@ast
Hepadnavirus integration: mech ...... oson in woodchuck liver tumors
@en
prefLabel
Hepadnavirus integration: mech ...... oson in woodchuck liver tumors
@ast
Hepadnavirus integration: mech ...... oson in woodchuck liver tumors
@en
P2093
P2860
P1433
P1476
Hepadnavirus integration: mech ...... oson in woodchuck liver tumors
@en
P2093
P2860
P304
P407
P577
1992-09-01T00:00:00Z