Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors - Wikidata - awgldk - TriplyDB

Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors

Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors

http://www.wikidata.org/entity/Q33936327

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High-throughput screening to enhance oncolytic virus immunotherapy Oncolytic viruses as anticancer vaccines Harnessing the Power of Onco-Immunotherapy with Checkpoint Inhibitors LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma.The role of epithelial plasticity in prostate cancer dissemination and treatment resistance Functional cloning of recurrence-specific antigens identifies molecular targets to treat tumor relapse.The profile of tumor antigens which can be targeted by immunotherapy depends upon the tumor's anatomical site.Variable epitope library carrying heavily mutated survivin-derived CTL epitope variants as a new class of efficient vaccine immunogen tested in a mouse model of breast cancer.Vesicular stomatitis virus oncolytic treatment interferes with tumor-associated dendritic cell functions and abrogates tumor antigen presentation.Mutated BRAF Emerges as a Major Effector of Recurrence in a Murine Melanoma Model After Treatment With Immunomodulatory Agents Gene and cell therapy for pancreatic cancer.Cytokine conditioning enhances systemic delivery and therapy of an oncolytic virus.Combination viroimmunotherapy with checkpoint inhibition to treat glioma, based on location-specific tumor profiling.Can the exome and the immunome converge on the design of efficient cancer vaccines?Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine.Antigen spreading-induced CD8+T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells.Novel therapies for the treatment of advanced prostate cancer.The efficacy versus toxicity profile of combination virotherapy and TLR immunotherapy highlights the danger of administering TLR agonists to oncolytic virus-treated mice Definitive Management of Oligometastatic Melanoma in a Murine Model Using Combined Ablative Radiation Therapy and Viral Immunotherapy Immunotherapy exposes cancer stem cell resistance and a new synthetic lethality Immunotherapeutic approaches to hepatocellular carcinoma treatment Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies.Detecting and targeting tumor relapse by its resistance to innate effectors at early recurrence.Immunogenicity of self tumor associated proteins is enhanced through protein truncation.Adoptive T cell therapy promotes the emergence of genomically altered tumor escape variants.Glioma virus therapies between bench and bedside.Replicating viral vectors for cancer therapy: strategies to synergize with host immune responses.Oncolytic virotherapy for renal cell carcinoma: a novel treatment paradigm?Cancer immunotherapy: a paradigm shift for prostate cancer treatment.Oncolytic virotherapy Prostate cancer vaccines.Oncolytic vaccines.Oncolytic viruses and their application to cancer immunotherapy Sorting Out Pandora's Box: Discerning the Dynamic Roles of Liver Microenvironment in Oncolytic Virus Therapy for Hepatocellular Carcinoma.The role of oncolytic virus immunotherapies to subvert cancer immune evasion.Targeting Melanoma with Cancer-Killing Viruses.Inhibitory Receptors Induced by VSV Viroimmunotherapy Are Not Necessarily Targets for Improving Treatment Efficacy.EMT, CSCs, and drug resistance: the mechanistic link and clinical implications.

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Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors

http://www.wikidata.org/entity/Q33936327

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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Nature Medicine

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Fiona Errington

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Hardev Pandha

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Jose Pulido

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Phonphimon Wongthida

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Richard Vile

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P2860

Potentiating cancer immunotherapy using an oncolytic virus

Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

The basics of epithelial-mesenchymal transition

Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer

Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate

The transcriptional repressor Snail promotes mammary tumor recurrence

T cell receptor antagonist peptides induce positive selection

Potent vesicular stomatitis virus-based avian influenza vaccines provide long-term sterilizing immunity against heterologous challenge.

Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins.

Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus.

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10.1038/NM.2390

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7

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Feorillo Galivo

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