VX680/MK-0457, a potent and selective Aurora kinase inhibitor, targets both tumor and endothelial cells in clear cell renal cell carcinoma.
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SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancersUpdate on aurora kinase inhibitors in gynecologic malignancies.Update on Aurora Kinase Targeted Therapeutics in Oncology.Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression.Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagyNetwork analysis of immunotherapy-induced regressing tumours identifies novel synergistic drug combinations.Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A functionA streamlined search technology for identification of synergistic drug combinations.RNA-seq reveals aurora kinase-driven mTOR pathway activation in patients with sarcomatoid metastatic renal cell carcinoma.Tanshinones suppress AURKA through up-regulation of miR-32 expression in non-small cell lung cancer.Ceftriaxone, an FDA-approved cephalosporin antibiotic, suppresses lung cancer growth by targeting Aurora B.Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer.Aurora kinase A activates the vacuolar H+-ATPase (V-ATPase) in kidney carcinoma cellsPreclinical validation of Aurora kinases-targeting drugs in osteosarcoma.Quercetin suppresses lung cancer growth by targeting Aurora B kinase.Targeted therapy for renal cell carcinoma: The next lap.Precision Subtypes of T Cell-Mediated Rejection Identified by Molecular Profiles.APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model.Effect of human flavin-containing monooxygenase 3 polymorphism on the metabolism of aurora kinase inhibitors.Silencing Aurora A leads to re-sensitization of breast cancer cells to Taxol through downregulation of SRC-mediated ERK and mTOR pathways.Novel multi‑kinase inhibitor, T03 inhibits Taxol‑resistant breast cancer.RIPK1-dependent cell death: a novel target of the Aurora kinase inhibitor Tozasertib (VX-680).
P2860
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P2860
VX680/MK-0457, a potent and selective Aurora kinase inhibitor, targets both tumor and endothelial cells in clear cell renal cell carcinoma.
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2010 nî lūn-bûn
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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
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2010年論文
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2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
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2010年论文
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name
VX680/MK-0457, a potent and se ...... ear cell renal cell carcinoma.
@ast
VX680/MK-0457, a potent and se ...... ear cell renal cell carcinoma.
@en
type
label
VX680/MK-0457, a potent and se ...... ear cell renal cell carcinoma.
@ast
VX680/MK-0457, a potent and se ...... ear cell renal cell carcinoma.
@en
prefLabel
VX680/MK-0457, a potent and se ...... ear cell renal cell carcinoma.
@ast
VX680/MK-0457, a potent and se ...... ear cell renal cell carcinoma.
@en
P2093
P2860
P1476
VX680/MK-0457, a potent and se ...... lear cell renal cell carcinoma
@en
P2093
Bin Tean Teh
Chao-Nan Qian
James H Resau
Jindong Chen
Min-Han Tan
Zhong-Fa Zhang
P2860
P304
P407
P50
P577
2010-05-20T00:00:00Z