Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. - Wikidata - awgldk - TriplyDB

Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence.

Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence.

http://www.wikidata.org/entity/Q33942306

about

Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking Genetic research on nicotine dependence will facilitate public health New mechanisms and perspectives in nicotine withdrawal Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence Symbiotic relationship of pharmacogenetics and drugs of abuse.Transcriptome sequencing of gene expression in the brain of the HIV-1 transgenic rat.Novel genes identified in a high-density genome wide association study for nicotine dependence Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions.Ethnic-specific genetic association of variants in the corticotropin-releasing hormone receptor 1 gene with nicotine dependence.The contribution of rare and common variants in 30 genes to risk nicotine dependence Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations Serotonin transporter and receptor genes significantly impact nicotine dependence through genetic interactions in both European American and African American smokers Genetics of GABAergic signaling in nicotine and alcohol dependence.Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence.Common and unique biological pathways associated with smoking initiation/progression, nicotine dependence, and smoking cessation.New insights into the genetics of addiction Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence.Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15 Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations.Regulation by nicotine of Gpr51 and Ntrk2 expression in various rat brain regions.A genomewide search finds major susceptibility loci for nicotine dependence on chromosome 10 in African Americans.Beta-arrestins 1 and 2 are associated with nicotine dependence in European American smokers.Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers.Nicotine response genetics in the zebrafish.Genome wide association for addiction: replicated results and comparisons of two analytic approaches Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American The role of 5-HT3 receptors in drug abuse and as a target for pharmacotherapy.GABA Receptors Genes Polymorphisms and Alcohol Dependence: No Evidence of an Association in an Italian Male Population GENES AS INSTRUMENTS FOR STUDYING RISK BEHAVIOR EFFECTS: AN APPLICATION TO MATERNAL SMOKING AND OROFACIAL CLEFTS A genetic instrumental variables analysis of the effects of prenatal smoking on birth weight: evidence from two samples.Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.Smoking and body weight: evidence using genetic instruments Assessing the impact of nicotine dependence genes on the risk of facial clefts: An example of the use of national registry and biobank data.The Role of the Habenula in Nicotine Addiction.Intergenerational continuity in parents' and adolescents' externalizing problems: The role of life events and their interaction with GABRA2.Genetics of nicotine dependence and pharmacotherapy.Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.Dopamine genes and nicotine dependence in treatment-seeking and community smokers.Overview of the pharmacogenomics of cigarette smoking.The Impact of Cigarette Quitting during Pregnancy on Other Prenatal Health Behaviors.

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P2860

Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence.

http://www.wikidata.org/entity/Q33942306

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Single- and multilocus allelic ...... ated with nicotine dependence.

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Grant Somes

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Jennie Z Ma

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Joke Beuten

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Karen M Crews

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Ming D Li

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Nancy J Williams

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Randolph T Dupont

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Robert C Elston

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Thomas J Payne

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P2860

Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.

PedCheck: a program for identification of genotype incompatibilities in linkage analysis

A pharmacologic strategy for the treatment of nicotine addiction

The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire

Substance abuse vulnerability loci: converging genome scanning data.

Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics.

A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population.

A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other.

The genetic epidemiology of smoking.

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

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