Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma. - Wikidata - awgldk - TriplyDB

Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma.

Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma.

http://www.wikidata.org/entity/Q33942561

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Tumor Targeting and Drug Delivery by Anthrax Toxin The Ins and Outs of Anthrax Toxin Obstructing toxin pathways by targeted pore blockage Bacillus anthracis edema factor substrate specificity: evidence for new modes of action Ratcheting up protein translocation with anthrax toxin Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers Anthrax toxin protective antigen integrates poly- -D-glutamate and pH signals to sense the optimal environment for channel formation Domain Flexibility Modulates the Heterogeneous Assembly Mechanism of Anthrax Toxin Protective Antigen Tailored ß-cyclodextrin blocks the translocation pores of binary exotoxins from C. botulinum and C. perfringens and protects cells from intoxication Functional truncated membrane pores.Subunit dimers of alpha-hemolysin expand the engineering toolbox for protein nanopores Anthrax toxin receptor drives protective antigen oligomerization and stabilizes the heptameric and octameric oligomer by a similar mechanism.Residue histidine 669 is essential for the catalytic activity of Bacillus anthracis lethal factor.Long-range stabilization of anthrax protective antigen upon binding to CMG2.Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins.A novel mechanism for antibody-based anthrax toxin neutralization: inhibition of prepore-to-pore conversion.Small molecule inhibitors of Bacillus anthracis protective antigen proteolytic activation and oligomerization.Charge requirements for proton gradient-driven translocation of anthrax toxin Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers Receptor binding enables botulinum neurotoxin B to sense low pH for translocation channel assembly.Supercharging protein complexes from aqueous solution disrupts their native conformations.Electrothermal supercharging of proteins in native electrospray ionization.Electrostatic ratchet in the protective antigen channel promotes anthrax toxin translocation.Host cell cytotoxicity and cytoskeleton disruption by CerADPr, an ADP-ribosyltransferase of Bacillus cereus G9241 Anthrax toxin-induced rupture of artificial lipid bilayer membranes.Anthrax lethal toxin co-complexes are stabilized by contacts between adjacent lethal factors.Peptide Probes Reveal a Hydrophobic Steric Ratchet in the Anthrax Toxin Protective Antigen Translocase.Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen.Anions in electrothermal supercharging of proteins with electrospray ionization follow a reverse Hofmeister series.The unfolding story of anthrax toxin translocation.Anthrax toxin protective antigen--insights into molecular switching from prepore to pore Multivalent Inhibitors of Channel-Forming Bacterial Toxins.The potential of toxin-based drug delivery systems for enhanced nucleic acid therapeutic delivery.Serum amyloid A 2.2 refolds into a octameric oligomer that slowly converts to a more stable hexamer.Electrothermal supercharging of proteins in native MS: effects of protein isoelectric point, buffer, and nanoESI-emitter tip size.The anthrax toxin channel: a barrel of LFs.Submicrometer Emitter ESI Tips for Native Mass Spectrometry of Membrane Proteins in Ionic and Nonionic Detergents.ANTXR1-bound PA63 forms oligomers ANTXR2-bound PA63 forms oligomers Advances in structure determination by cryo-EM to unravel membrane-spanning pore formation

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Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma.

http://www.wikidata.org/entity/Q33942561

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Role of the protective antigen ...... toxin stabilization in plasma.

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Role of the protective antigen ...... toxin stabilization in plasma.

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Role of the protective antigen ...... toxin stabilization in plasma.

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Role of the protective antigen ...... toxin stabilization in plasma.

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Role of the protective antigen ...... toxin stabilization in plasma.

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Role of the protective antigen ...... toxin stabilization in plasma.

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J.JMB.2010.04.041

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Journal of Molecular Biology

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Role of the protective antigen ...... toxin stabilization in plasma.

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P2093

Alexander F Kintzer

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Ali Abdul-Gader

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Andrew J Miles

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B A Wallace

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Bryan A Krantz

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Evan R Williams

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Harry J Sterling

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Iok I Tang

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P2860

Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin

Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation

Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen

Contribution of individual toxin components to virulence of Bacillus anthracis

Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process

Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor

Crystal structure of the anthrax lethal factor

The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes

Crystal structure of the anthrax toxin protective antigen

SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields

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