Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR. - Wikidata - awgldk - TriplyDB

Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR.

Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR.

http://www.wikidata.org/entity/Q33943471

about

Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactions Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1 Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring.Integrated analysis of copy number variation and genome-wide expression profiling in colorectal cancer tissues Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway 14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity.G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression Quantitative reconstitution of mitotic CDK1 activation in somatic cell extracts.Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.Mitotic phosphorylation of Cdc25B Ser321 disrupts 14-3-3 binding to the high affinity Ser323 site Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progression.DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression.Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle.Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila.MicroRNA-141 is downregulated in human renal cell carcinoma and regulates cell survival by targeting CDC25B.Cyclin A2 promotes DNA repair in the brain during both development and aging.miR-223 functions as a potent tumor suppressor of the Lewis lung carcinoma cell line by targeting insulin-like growth factor-1 receptor and cyclin-dependent kinase 2 Premature chromosome condensation in humans associated with microcephaly and mental retardation: a novel autosomal recessive condition.Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest.LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells.MicroRNA-211, a direct negative regulator of CDC25B expression, inhibits triple-negative breast cancer cells' growth and migration.Role of methamphetamine on glioblastoma cytotoxicity induced by doxorubicin and methotrexate.Multiple melanoma susceptibility factors function in an ultraviolet radiation response pathway in skin.Human Cdc25A phosphatase has a non-redundant function in G2 phase by activating Cyclin A-dependent kinases.Inappropriate activation of cyclin-dependent kinases by the phosphatase Cdc25b results in premature mitotic entry and triggers a p53-dependent checkpoint.The dual specificity phosphatase Cdc25B, but not the closely related Cdc25C, is capable of inhibiting cellular proliferation in a manner dependent upon its catalytic activity.Inhibition of S/G2 phase CDK4 reduces mitotic fidelity.Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry.microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells.New perspectives of cobalt tris(bipyridine) system: anti-cancer effect and its collateral sensitivity towards multidrug-resistant (MDR) cancers.MAPK pathway activation delays G2/M progression by destabilizing Cdc25B.Cdc25B activity is regulated by 14-3-3.The Efficacy and Underlying Mechanism of Moxibustion in Preventing Cognitive Impairment: A Systematic Review of Animal Studies.Involvement of protein kinase B/AKT in early development of mouse fertilized eggs.

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Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR.

http://www.wikidata.org/entity/Q33943471

description

2001 nî lūn-bûn

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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2001 թվականի փետրվարին հրատարակված գիտական հոդված

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2001年の論文

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Cdc25-dependent activation of ...... ells independently of ATM/ATR.

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Cdc25-dependent activation of ...... ells independently of ATM/ATR.

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Forrest A

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Gabrielli B

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Goldstone S

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Pavey S

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Sinnamon J

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P2860

p53 regulates a G2 checkpoint through cyclin B1

Nuclear localization of cyclin B1 controls mitotic entry after DNA damage

Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis

The G2-phase DNA-damage checkpoint

A cyclin D-Cdk4 activity required for G2 phase cell cycle progression is inhibited in ultraviolet radiation-induced G2 phase delay

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2

Caffeine inhibits the checkpoint kinase ATM

Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases

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10.1038/SJ.ONC.1204177

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1032733736

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11314027

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