Direct recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function.
about
The WT hemochromatosis protein HFE inhibits CD8⁺ T-lymphocyte activationThe Tritope Model for restrictive recognition of antigen by T-cells II. Implications for ontogeny, evolution and physiologyMonitoring the T-cell receptor repertoire at single-clone resolution.Back to the fold: T cell recognition of HFE, a MHC class Ib molecule that regulates iron metabolismMolecular identification of an MHC-independent ligand recognized by a human {alpha}/{beta} T-cell receptor.An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection.Birth Cohort, Age, and Sex Strongly Modulate Effects of Lipid Risk Alleles Identified in Genome-Wide Association Studies.Impact of hemochromatosis gene (HFE) mutations on epithelial ovarian cancer risk and prognosisMolecular insights into the pathogenesis of hereditary haemochromatosisCis interactions of immunoreceptors with MHC and non-MHC ligands.Characterization of a novel nonclassical T cell clone with broad reactivity against human renal cell carcinomas.The unfolded protein response in hereditary haemochromatosis.The emerging role of HLA-E-restricted CD8+ T lymphocytes in the adaptive immune response to pathogens and tumors.Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice.Understanding the complexity and malleability of T-cell recognition.The role of MHC class Ib-restricted T cells during infection.The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune systemHuman Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections?Immune parameters to consider when choosing T-cell receptors for therapy.Function of the hemochromatosis protein HFE: Lessons from animal models.Conservation of sequence motifs suggests that the nonclassical MHC class I lineages CD1/PROCR and UT were established before the emergence of tetrapod species.Loss of central and peripheral CD8+ T-cell tolerance to HFE in mouse models of human familial hemochromatosis.A high-fat diet modulates iron metabolism but does not promote liver fibrosis in hemochromatotic Hjv⁻/⁻ mice.
P2860
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P2860
Direct recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Direct recognition by alphabet ...... t antigen-presenting function.
@ast
Direct recognition by alphabet ...... t antigen-presenting function.
@en
type
label
Direct recognition by alphabet ...... t antigen-presenting function.
@ast
Direct recognition by alphabet ...... t antigen-presenting function.
@en
prefLabel
Direct recognition by alphabet ...... t antigen-presenting function.
@ast
Direct recognition by alphabet ...... t antigen-presenting function.
@en
P2093
P2860
P50
P356
P1476
Direct recognition by alphabet ...... ut antigen-presenting function
@en
P2093
Faridabano Nato
Florent Ginhoux
François A Lemonnier
Hélène Coppin
Hüseyin Firat
Jean Kanellopoulos
Madeleine Cochet
Marie Paule Roth
Nihay Laham
Olivier Danos
P2860
P304
12855-12860
P356
10.1073/PNAS.0502309102
P407
P577
2005-08-25T00:00:00Z