Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization
about
HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual.HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal AntibodiesImmunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection.Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.Breakthrough Virus Neutralization Resistance as a Correlate of Protection in a Nonhuman Primate Heterologous Simian Immunodeficiency Virus Vaccine Challenge Study.Accurate predictions of population-level changes in sequence and structural properties of HIV-1 Env using a volatility-controlled diffusion model.Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization.Learning the Relationship between the Primary Structure of HIV Envelope Glycoproteins and Neutralization Activity of Particular Antibodies by Using Artificial Neural Networks.Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.Peripheral Membrane Interactions Boost the Engagement by an Anti-HIV-1 Broadly Neutralizing Antibody.Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimerDNA prime/protein boost vaccination elicits robust humoral response in rhesus macaques using oligomeric simian immunodeficiency virus envelope and Advax delta inulin adjuvant.Neutralization of Virus Infectivity by Antibodies: Old Problems in New Perspectives.Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design.Trimerization of the HIV Transmembrane Domain in Lipid Bilayers Modulates Broadly Neutralizing Antibody Binding.Functional Stability of HIV-1 Envelope Trimer Affects Accessibility to Broadly Neutralizing Antibodies at its Apex.Optimization of the EC26-2A4 epitope in the gp41 membrane proximal external region (MPER) targeted by neutralizing antibodies from an elite controller.FUNCTIONAL OPTIMIZATION OF BROADLY NEUTRALIZING HIV-1 ANTIBODY 10E8 BY PROMOTING MEMBRANE INTERACTIONS.The development of HIV vaccines targeting gp41 membrane-proximal external region (MPER): challenges and prospects.Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.
P2860
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P2860
Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Antibody to gp41 MPER alters f ...... ithout complete neutralization
@ast
Antibody to gp41 MPER alters f ...... ithout complete neutralization
@en
type
label
Antibody to gp41 MPER alters f ...... ithout complete neutralization
@ast
Antibody to gp41 MPER alters f ...... ithout complete neutralization
@en
prefLabel
Antibody to gp41 MPER alters f ...... ithout complete neutralization
@ast
Antibody to gp41 MPER alters f ...... ithout complete neutralization
@en
P2860
P1433
P1476
Antibody to gp41 MPER alters f ...... ithout complete neutralization
@en
P2093
Daniel P Leaman
Michael B Zwick
P2860
P304
P356
10.1371/JOURNAL.PPAT.1004271
P577
2014-07-24T00:00:00Z