Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).
about
Repurposing metformin: an old drug with new tricks in its binding pocketsCurrent understanding of metformin effect on the control of hyperglycemia in diabetesExercise training plus metformin, but not exercise training alone, decreases insulin production and increases insulin clearance in adults with prediabetes.Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression.Dissecting the role of AMP-activated protein kinase in human diseases.Activation of AMP-activated protein kinase by metformin protects human coronary artery endothelial cells against diabetic lipoapoptosisMetformin activates AMP-activated protein kinase by promoting formation of the αβγ heterotrimeric complex.Therapeutic Concentrations of Metformin: A Systematic Review.Metformin Changes the Relationship between Blood Monocyte Toll-Like Receptor 4 Levels and Nonalcoholic Fatty Liver Disease-Ex Vivo StudiesThe desert gerbil Psammomys obesus as a model for metformin-sensitive nutritional type 2 diabetes to protect hepatocellular metabolic damage: Impact of mitochondrial redox stateActivation of the cAMP-PKA pathway Antagonizes Metformin Suppression of Hepatic Glucose Production.Visualization of Compartmentalized Kinase Activity Dynamics Using Adaptable BimKARs.The Effects of Metformin on Obesity-Induced Dysfunctional RetinasEndotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity.Metformin: A Hopeful Promise in Aging Research.AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.New insights into the anti-diabetic actions of metformin: from the liver to the gut.A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance.Regulation of hepatic glucose metabolism in health and disease.Hyperglucagonemia Mitigates the Effect of Metformin on Glucose Production in Prediabetes.Metformin Suppressed CXCL8 Expression and Cell Migration in HEK293/TLR4 Cell Line.Expression profile analysis of long non-coding RNAs involved in the metformin-inhibited gluconeogenesis of primary mouse hepatocytes.Metformin extends C. elegans lifespan through lysosomal pathway.Metformin-induced mitochondrial function and ABCD2 up-regulation in X-linked adrenoleukodystrophy involves AMP-activated protein kinase.Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice.Itraconazole attenuates hepatic gluconeogenesis and promotes glucose uptake by regulating AMPK pathway.Effects of metformin treatment on blood leptin and ghrelin levels in patients with type 2 diabetes mellitus.Urinary Metabolomic Profiling in Zucker Diabetic Fatty Rats with Type 2 Diabetes Mellitus Treated with Glimepiride, Metformin, and Their Combination.Why AMPK agonists not known to be stressors may surprisingly contribute to miscarriage or hinder IVF/ART.Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus.
P2860
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P2860
Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Low concentrations of metformi ...... tivated protein kinase (AMPK).
@ast
Low concentrations of metformi ...... tivated protein kinase (AMPK).
@en
type
label
Low concentrations of metformi ...... tivated protein kinase (AMPK).
@ast
Low concentrations of metformi ...... tivated protein kinase (AMPK).
@en
prefLabel
Low concentrations of metformi ...... tivated protein kinase (AMPK).
@ast
Low concentrations of metformi ...... tivated protein kinase (AMPK).
@en
P2093
P2860
P356
P1476
Low concentrations of metformi ...... tivated protein kinase (AMPK).
@en
P2093
Evan Chang
Fredric E Wondisford
Katherine Beckwith-Fickas
Lishou Xiong
Robert N Cole
Sally Radovick
Shumei Meng
P2860
P304
20435-20446
P356
10.1074/JBC.M114.567271
P407
P577
2014-07-01T00:00:00Z