Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulation
about
Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogationSynthetic biology devices for in vitro and in vivo diagnosticsEnabling functional genomics with genome engineeringThe epigenome: the next substrate for engineeringNucleosome distortion as a possible mechanism of transcription activation domain functionChromatin regulation at the frontier of synthetic biologyThe appeasement of Doug: a synthetic approach to enhancer biology.Dynamics of epigenetic regulation at the single-cell level.Measurements of translation initiation from all 64 codons in E. coli.Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.Core concept: Synthetic biology-change, accelerated.Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds.Inducible suppression of global translation by overuse of rare codons.Signal-to-Noise Ratio Measures Efficacy of Biological Computing Devices and Circuits.Digital logic circuits in yeast with CRISPR-dCas9 NOR gatesBuild to understand: synthetic approaches to biologyEditing the epigenome: technologies for programmable transcription and epigenetic modulation.Genomic targeting of epigenetic probes using a chemically tailored Cas9 system.Computational and experimental methods to decipher the epigenetic codeEpigenetic roots of immunologic disease and new methods for examining chromatin regulatory pathways.The timing of transcriptional regulation in synthetic gene circuits.From noise to synthetic nucleoli: can synthetic biology achieve new insights?Transcriptional regulators form diverse groups with context-dependent regulatory functions.Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.From profiles to function in epigenomics.The INO80 Complex Requires the Arp5-Ies6 Subcomplex for Chromatin Remodeling and Metabolic Regulation.Integrating gene synthesis and microfluidic protein analysis for rapid protein engineering.DNA sense-and-respond protein modules for mammalian cells.Sequence-targeted nucleosome sliding in vivo by a hybrid Chd1 chromatin remodelerMolecular structures guide the engineering of chromatin.Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner.Brave new epigenomes: the dawn of epigenetic engineering.MOLECULAR BIOLOGY. A unifying model of epigenetic regulation.Current status and perspectives of genome editing technology for microalgae.Transcriptional precision and accuracy in development: from measurements to models and mechanisms.Epigenetic editing: How cutting-edge targeted epigenetic modification might provide novel avenues for autoimmune disease therapy.Promoter and Terminator Discovery and Engineering.Epigenome editing made easy.Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation.Neuroepigenetic Editing.
P2860
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P2860
Using targeted chromatin regulators to engineer combinatorial and spatial transcriptional regulation
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Using targeted chromatin regul ...... ial transcriptional regulation
@ast
Using targeted chromatin regul ...... ial transcriptional regulation
@en
type
label
Using targeted chromatin regul ...... ial transcriptional regulation
@ast
Using targeted chromatin regul ...... ial transcriptional regulation
@en
prefLabel
Using targeted chromatin regul ...... ial transcriptional regulation
@ast
Using targeted chromatin regul ...... ial transcriptional regulation
@en
P2093
P2860
P1433
P1476
Using targeted chromatin regul ...... ial transcriptional regulation
@en
P2093
Ahmad S Khalil
Albert J Keung
Caleb J Bashor
James J Collins
Szilvia Kiriakov
P2860
P304
P356
10.1016/J.CELL.2014.04.047
P407
P577
2014-07-01T00:00:00Z