The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: distinct mechanisms?
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Pregnenolone rescues schizophrenia-like behavior in dopamine transporter knockout mice.Battery of behavioral tests in mice to study postoperative delirium.Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophreniaTiO2 nanoparticles induced hippocampal neuroinflammation in miceNeuroactive Steroids are Altered in Schizophrenia and Bipolar Disorder: Relevance to Pathophysiology and TherapeuticsAntipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotectionPregnenolone sulfate normalizes schizophrenia-like behaviors in dopamine transporter knockout mice through the AKT/GSK3β pathway.GABA(A) receptors and their associated proteins: implications in the etiology and treatment of schizophrenia and related disorders.Neurosteroid transport by the organic solute transporter OSTα-OSTβ.Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.A role for picomolar concentrations of pregnenolone sulfate in synaptic activity-dependent Ca2+ signaling and CREB activationNeuroprotection by the synthetic neurosteroid enantiomers ent-PREGS and ent-DHEAS against Aβ₂₅₋₃₅ peptide-induced toxicity in vitro and in vivo in micePregnenolone sulfate and its enantiomer: differential modulation of memory in a spatial discrimination task using forebrain NMDA receptor deficient miceGene-expression changes in cerium chloride-induced injury of mouse hippocampus.Immunotherapy of cerebrovascular amyloidosis in a transgenic mouse modelDecreased GABA receptor in the cerebral cortex of epileptic rats: effect of Bacopa monnieri and Bacoside-A.Alzheimer's disease drugs: an application of the hormetic dose-response model.Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.ent-Steroids: novel tools for studies of signaling pathways.The Singapore flagship programme in translational and clinical research in psychosis.Structure-activity relationship studies on neuroactive steroids in memory, alcohol and stress-related functions: a crucial benefit from endogenous level analysis.Nootropic activity of lipid-based extract of Bacopa monniera Linn. compared with traditional preparation and extracts.Neurosteroids enhance spontaneous glutamate release in hippocampal neurons. Possible role of metabotropic sigma1-like receptors.Critical role of the plasma membrane for expression of mammalian mitochondrial side chain cleavage activity in yeast.Role of neuroactive steroid allopregnanolone in antipsychotic-like action of olanzapine in rodents.NMDA potentiation by visible light in the presence of a fluorescent neurosteroid analogue.Adenosine receptor antagonists including caffeine alter fetal brain development in mice.Mitochondrial involvement in memory impairment induced by scopolamine in rats.Synthetic nat- or ent-steroids in as few as five chemical steps from epichlorohydrin.Learning and cognitive deficits in hypoxic neonatal rats intensified by BAX mediated apoptosis: protective role of glucose, oxygen, and epinephrine.Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia.Study on action mechanism of 1-(4-methoxy-2-methylphenyl)piperazine (MMPP) in acquisition, formation, and consolidation of memory in mice.The toxicological effects in brain of mice following exposure to cerium chloride.Signal pathway of hippocampal apoptosis and cognitive impairment of mice caused by cerium chloride.Long-term exposure to extremely low-frequency magnetic fields impairs spatial recognition memory in mice.Neurosteroids in Schizophrenia: Pathogenic and Therapeutic Implications.Neurosteroid Transport in the Brain: Role of ABC and SLC Transporters.Steroids and Brain, a Rising Bio-Medical Domain: a Perspective.
P2860
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P2860
The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: distinct mechanisms?
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The synthetic enantiomer of pr ...... nterpart: distinct mechanisms?
@ast
The synthetic enantiomer of pr ...... nterpart: distinct mechanisms?
@en
type
label
The synthetic enantiomer of pr ...... nterpart: distinct mechanisms?
@ast
The synthetic enantiomer of pr ...... nterpart: distinct mechanisms?
@en
prefLabel
The synthetic enantiomer of pr ...... nterpart: distinct mechanisms?
@ast
The synthetic enantiomer of pr ...... nterpart: distinct mechanisms?
@en
P2093
P2860
P356
P1476
The synthetic enantiomer of pr ...... nterpart: distinct mechanisms?
@en
P2093
E E Baulieu
N Ladurelle
P2860
P304
14033-14037
P356
10.1073/PNAS.241503698
P407
P50
P577
2001-11-01T00:00:00Z