Energy conformation study of Met-enkephalin and its D-Ala2 analogue and their resemblance to rigid opiates
about
Synthesis and conformational analysis of a series of galactosyl enkephalin analogues showing high analgesic activity.Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway.Nuclear Overhauser effects in linear peptides. A low-temperature 500 MHz study of Met-enkephalin.NOE data at 500 MHz reveal the proximity of phenyl and tyrosine rings in enkephalin.Stereochemical basis for a unified structure activity theory of aromatic and heterocyclic rings in selected opioids and opioid peptidesAmide-to-ester substitution allows fine-tuning of the cyclopeptide conformational ensemble.Quantum chemical studies of molecular features and receptor interactions that modulate opiate agonist and antagonist activity.A stereochemically-constrained enkephalin analog. alpha-Aminoisobutyryl2 methionine5 enkephalinamide.Enkephalin analogs. Introduction of sterochemical constraints, metal binding sites and fluorescent groups.X-ray diffraction studies of enkephalins. Crystal structure of [(4'-bromo) Phe4,Leu5]enkephalin.Molecular-dynamics simulations of [Met5]- and [D-Ala2,Met5]-enkephalins. Biological implication of monomeric folded and dimeric unfolded conformationsConformational analysis of the Ca(2+)-bound opioid peptides: implications for ligand-receptor interaction.Linear and Cyclic Depsipeptidomimetics with β-Lactam Cores: A Class of New αv β3 Integrin Receptor Inhibitors.Investigation of conformational equilibrium of polypeptides by internal coordinate stochastic dynamics. Met5-enkephalin.A fast algorithm for the interactive docking maneuver with flexible macromolecules and probes.
P2860
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P2860
Energy conformation study of Met-enkephalin and its D-Ala2 analogue and their resemblance to rigid opiates
description
1978 nî lūn-bûn
@nan
1978 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1978 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1978年の論文
@ja
1978年論文
@yue
1978年論文
@zh-hant
1978年論文
@zh-hk
1978年論文
@zh-mo
1978年論文
@zh-tw
1978年论文
@wuu
name
Energy conformation study of M ...... r resemblance to rigid opiates
@ast
Energy conformation study of M ...... r resemblance to rigid opiates
@en
type
label
Energy conformation study of M ...... r resemblance to rigid opiates
@ast
Energy conformation study of M ...... r resemblance to rigid opiates
@en
prefLabel
Energy conformation study of M ...... r resemblance to rigid opiates
@ast
Energy conformation study of M ...... r resemblance to rigid opiates
@en
P2860
P356
P1476
Energy conformation study of M ...... r resemblance to rigid opiates
@en
P2860
P356
10.1073/PNAS.75.1.7
P407
P577
1978-01-01T00:00:00Z