Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs
about
A novel shuttle protein binds to RNA helicase A and activates the retroviral constitutive transport elementSpecific interaction between RNA helicase A and Tap, two cellular proteins that bind to the constitutive transport element of type D retrovirusTAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architectureMatrin 3 is a co-factor for HIV-1 Rev in regulating post-transcriptional viral gene expressionPrediction of structural domains of TAP reveals details of its interaction with p15 and nucleoporinsRole of polypyrimidine tract binding protein in the function of the hepatitis B virus posttranscriptional regulatory element.Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexesICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway.The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substratesKaryopherin beta 2B participates in mRNA export from the nucleus.NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells.Mex67p of Schizosaccharomyces pombe interacts with Rae1p in mediating mRNA exportThe spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctionsIdentification and characterization of the mouse nuclear export factor (Nxf) family membersThe structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domainBinding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export.The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p.Sam68, RNA helicase A and Tap cooperate in the post-transcriptional regulation of human immunodeficiency virus and type D retroviral mRNAU2AF participates in the binding of TAP (NXF1) to mRNAUsing viral species specificity to define a critical protein/RNA interaction surfaceREF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complexTap and NXT promote translation of unspliced mRNA.Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex.NXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins.An element in the 3' untranslated region of human LINE-1 retrotransposon mRNA binds NXF1(TAP) and can function as a nuclear export element.Modular organization and combinatorial energetics of proline-tyrosine nuclear localization signalsEpstein-Barr virus EB2 protein exports unspliced RNA via a Crm-1-independent pathway.Adenovirus late gene expression does not require a Rev-like nuclear RNA export pathway.Evidence for nucleic acid binding ability and nucleosome association of Bombyx mori nucleopolyhedrovirus BRO proteinsRous sarcoma virus DR posttranscriptional elements use a novel RNA export pathway.Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr.Retroviral constitutive transport element evolved from cellular TAP(NXF1)-binding sequences.Nuclear import by karyopherin-βs: recognition and inhibitionTrimethylguanosine capping selectively promotes expression of Rev-dependent HIV-1 RNAs.Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling.Nuclear export of mRNA.The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67pNXF1/p15 heterodimers are essential for mRNA nuclear export in DrosophilaSmall bristles, the Drosophila ortholog of NXF-1, is essential for mRNA export throughout development
P2860
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P2860
Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Identification of novel import ...... of the type D retrovirus mRNAs
@ast
Identification of novel import ...... of the type D retrovirus mRNAs
@en
type
label
Identification of novel import ...... of the type D retrovirus mRNAs
@ast
Identification of novel import ...... of the type D retrovirus mRNAs
@en
prefLabel
Identification of novel import ...... of the type D retrovirus mRNAs
@ast
Identification of novel import ...... of the type D retrovirus mRNAs
@en
P2093
P2860
P356
P1476
Identification of novel import ...... of the type D retrovirus mRNAs
@en
P2093
P2860
P304
P356
10.1128/MCB.19.9.6306
P407
P577
1999-09-01T00:00:00Z