Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death
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Mitochondrial Redox Signaling and Tumor ProgressionThe Role of NOX4 and TRX2 in Angiogenesis and Their Potential Cross-Talk.ASK1-dependent endothelial cell activation is critical in ovarian cancer growth and metastasis.A Novel ASK Inhibitor AGI-1067 Inhibits TLR-4-Mediated Activation of ASK1 by Preventing Dissociation of Thioredoxin from ASK1.Molecular Skin Surface-Based Transformation Visualization between Biological Macromolecules.pH-dependent general base catalyzed activation rather than isocyanate liberation may explain the superior anticancer efficacy of laromustine compared to related 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine prodrugs.Critical in vivo roles of WNT10A in wound healing by regulating collagen expression/synthesis in WNT10A-deficient mice.
P2860
Q26749592-3A6E0A63-5BA8-48F1-A7F9-C5689D89D877Q33845086-B8EA24D4-E9D3-4C42-8AF1-D1F3585F904FQ42269997-1641858D-F116-48F9-B2B9-7DDC05A2A5B9Q42291031-E65F6BF4-628C-47D6-99D2-686AEB683140Q43092964-72B12AB8-EF34-4C6F-B1CD-F088A5EF0115Q46346689-DDADA64B-F6B9-4518-B39D-E6EBA863034DQ55111743-EF6BAB58-BAE0-4FD7-B030-29FC08608E9A
P2860
Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Carbamoylating activity associ ...... pendent endothelial cell death
@ast
Carbamoylating activity associ ...... pendent endothelial cell death
@en
type
label
Carbamoylating activity associ ...... pendent endothelial cell death
@ast
Carbamoylating activity associ ...... pendent endothelial cell death
@en
prefLabel
Carbamoylating activity associ ...... pendent endothelial cell death
@ast
Carbamoylating activity associ ...... pendent endothelial cell death
@en
P2093
P2860
P1433
P1476
Carbamoylating activity associ ...... pendent endothelial cell death
@en
P2093
Alexandra Praggastis
Dylan J Cincotta
Huanjiao Jenny Zhou
Roxanne Ghazvinian
Weidong Ji
Yonghao Li
P2860
P304
P356
10.1371/JOURNAL.PONE.0103224
P407
P577
2014-07-28T00:00:00Z