Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17.
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RBM4 interacts with an intronic element and stimulates tau exon 10 inclusionRNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice siteRegulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72.Role of RNA structure in regulating pre-mRNA splicingFunctional MAPT haplotypes: bridging the gap between genotype and neuropathologySRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategySplicing in action: assessing disease causing sequence changesMutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 betaThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetInvited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimagingTargeting mRNA for Alzheimer's and related dementias.RNA structure modulates splicing efficiency at the human immunodeficiency virus type 1 major splice donorIdentification of tau stem loop RNA stabilizers.Alternative promoters influence alternative splicing at the genomic level.Alternative splicing of exon 10 in the tau gene as a target for treatment of tauopathies.Alternative splicing enriched cDNA libraries identify breast cancer-associated transcriptsThe splice of life: alternative splicing and neurological disease.Adaptive alternative splicing correlates with less environmental risk of parkinsonism.Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells.Structural and functional analysis of the Rous Sarcoma virus negative regulator of splicing and demonstration of its activation by the 9G8 SR proteinBottom-up design of small molecules that stimulate exon 10 skipping in mutant MAPT pre-mRNAPSF: nuclear busy-body or nuclear facilitator?Genomic variants in exons and introns: identifying the splicing spoilers.Selecting for functional alternative splices in ESTs.RNA Structures as Mediators of Neurological Diseases and as Drug Targets.Larva-mediated chalkbrood resistance-associated single nucleotide polymorphism markers in the honey bee Apis mellifera.Influence of RNA secondary structure on the pre-mRNA splicing process.Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia.Polypyrimidine track-binding protein binding downstream of caspase-2 alternative exon 9 represses its inclusion.Tau alternative splicing and frontotemporal dementia.Identification of novel splice variants and exons of human endothelial cell-specific chemotaxic regulator (ECSCR) by bioinformatics analysis.A SNP (g.358A > T) at intronic region of CD9 molecule of crossbred bulls may associate with spermatozoal motility.Altered expression of RNA splicing proteins in Alzheimer's disease patients: evidence from two microarray studies.Tau mutations in neurodegenerative diseases.PSF suppresses tau exon 10 inclusion by interacting with a stem-loop structure downstream of exon 10.The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neuronsIntron retention resulting from a silent mutation in the VWF gene that structurally influences the 5' splice site.Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing.Targeting a pre-mRNA structure with bipartite antisense molecules modulates tau alternative splicing.Srp20 regulates TrkB pre-mRNA splicing to generate TrkB-Shc transcripts with implications for Alzheimer's disease.
P2860
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P2860
Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Aberrant splicing of tau pre-m ...... onism linked to chromosome 17.
@ast
Aberrant splicing of tau pre-m ...... onism linked to chromosome 17.
@en
type
label
Aberrant splicing of tau pre-m ...... onism linked to chromosome 17.
@ast
Aberrant splicing of tau pre-m ...... onism linked to chromosome 17.
@en
prefLabel
Aberrant splicing of tau pre-m ...... onism linked to chromosome 17.
@ast
Aberrant splicing of tau pre-m ...... onism linked to chromosome 17.
@en
P2093
P2860
P1476
Aberrant splicing of tau pre-m ...... onism linked to chromosome 17.
@en
P2093
P2860
P304
P356
10.1128/MCB.20.11.4036-4048.2000
P407
P577
2000-06-01T00:00:00Z