p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
about
Hallmarks of cancer and AU-rich elements5-Azacytidine enhances the radiosensitivity of CNE2 and SUNE1 cells in vitro and in vivo possibly by altering DNA methylationPhysiological networks and disease functions of RNA-binding protein AUF1The molecular balancing act of p16(INK4a) in cancer and aging.The cytokine IL-6 reactivates breast stromal fibroblasts through transcription factor STAT3-dependent up-regulation of the RNA-binding protein AUF1.p16(INK4A) positively regulates p21(WAF1) expression by suppressing AUF1-dependent mRNA decay.Combining small molecules for cell reprogramming through an interatomic analysis.An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2.Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer.PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells.p16INK4A represses breast stromal fibroblasts migration/invasion and their VEGF-A-dependent promotion of angiogenesis through Akt inhibition.Exploring the RNA world in hematopoietic cells through the lens of RNA-binding proteins.TLR9 re-expression in cancer cells extends the S-phase and stabilizes p16(INK4a) protein expressionThe cyclin-dependent kinase inhibitor p16INK4a physically interacts with transcription factor Sp1 and cyclin-dependent kinase 4 to transactivate microRNA-141 and microRNA-146b-5p spontaneously and in response to ultraviolet light-induced DNA damage.Cyclin D1-a prognostic marker in oropharyngeal squamous cell carcinoma that is tightly associated with high-risk human papillomavirus status.p16(INK4A) inhibits the pro-metastatic potentials of osteosarcoma cells through targeting the ERK pathway and TGF-β1.MicroRNA-141 and microRNA-146b-5p inhibit the prometastatic mesenchymal characteristics through the RNA-binding protein AUF1 targeting the transcription factor ZEB1 and the protein kinase AKTDesferrioxamine attenuates doxorubicin-induced acute cardiotoxicity through TFG-β/Smad p53 pathway in rat model.P16(INK4A) is required for cisplatin resistance in cervical carcinoma SiHa cells.A Multi-Locus Genetic Risk Score for Primary Open-Angle Glaucoma (POAG) Variants Is Associated with POAG Risk in a Mediterranean Population: Inverse Correlations with Plasma Vitamin C and E Concentrations.5-aza-2'-deoxycytidine, a DNA methylation inhibitor, attenuates hyperoxia-induced lung fibrosis via re-expression of P16 in neonatal rats.p16INK4A enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction.Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity.PAC exhibits potent anti-colon cancer properties through targeting cyclin D1 and suppressing epithelial-to-mesenchymal transition.p16INK4A induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1.
P2860
Q26744134-38C56487-FB69-47A0-A036-04CCFE98619BQ27312329-13924013-A64C-4DA0-A385-BA0A3EB64B99Q27693879-E90569DA-B6FE-4D88-A790-177FB6944B55Q34038585-1CA9AE05-2DBB-4FD1-A74A-C64713DCFEEDQ34467457-B7A83E38-6D1A-469C-B427-C0FAB59F623EQ34875568-183CA6A8-8EB4-4170-961C-5D1486A0E1D7Q34993880-38C13B13-EACD-417D-B3D5-B33C41A0AEC5Q35920986-1796CA49-7740-4A85-AB10-A4822A36D9DEQ36006304-F19E3B86-385D-40FB-95B6-06E0F52BCEF9Q36087902-074E3268-F325-4AE5-BCC2-8457D8B78FFBQ36520748-5209CB54-53D7-48CB-BC6F-802AC57EEBB3Q36751314-180FF2D2-F0B1-4B17-A52A-108D1D3BEFC4Q37150541-34577F8E-4F2F-49AC-A515-EA4CA67D826DQ37368732-01FA796C-ABEB-46CE-9678-258A473D2539Q37393146-ECB81F3B-BF9B-40C8-B643-D484AF9C65A8Q38904937-4A0EAEBE-CFAB-4A41-B58C-687DDE19C3F2Q42015120-A19C7A33-F069-4285-A696-1AE8FFF61444Q42138668-08DC72BE-2EB1-4A85-8E29-FCD7C6294006Q43128818-C283E101-9A70-436B-848F-CE6200F36829Q47101176-6497AD94-FF5F-462B-9A47-23FFD9E31476Q47373591-FB51E7FA-27B0-41BD-AABA-5BEE4630F37BQ48218608-EA9C67BA-DE28-4A26-9091-5ED45D0082A0Q50352951-71E826F4-9EDB-47C6-9C4B-2B1E91557C40Q51499892-A12F158E-49C4-4EEE-BF0C-352B71BF40D6Q51532861-B5977A7E-F42E-48C6-A273-7DB4C07B0955
P2860
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
@ast
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
@en
type
label
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
@ast
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
@en
prefLabel
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
@ast
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1.
@en
P2093
P2860
P1433
P1476
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1
@en
P2093
Abdelilah Aboussekhra
Albandary Al-Bakheet
Huda H Al-Khalaf
Maher Al-Saif
Namik Kaya
Nujoud Al-Yousef
Siti-Faujiah Hendrayani
P2860
P304
P356
10.1371/JOURNAL.PONE.0021111
P407
P577
2011-07-20T00:00:00Z