Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate
about
Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factorsSox6 directly silences epsilon globin expression in definitive erythropoiesis.Wnt signaling in cartilage development and diseases: lessons from animal studiesInduction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactionsArid5a cooperates with Sox9 to stimulate chondrocyte-specific transcriptionFunctional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritisdelta-EF1 is a negative regulator of Ihh in the developing growth plate.The HMG-box transcription factor Sox4b is required for pituitary expression of gata2a and specification of thyrotrope and gonadotrope cells in zebrafish.An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine EmbryosSynovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilageRab23 regulates differentiation of ATDC5 chondroprogenitor cells.The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesisRepression of SOX6 transcriptional activity by SUMO modification.Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutationVertebrate skeletogenesisGenetics and function of neocortical GABAergic interneurons in neurodevelopmental disordersSystems genetics analysis of mouse chondrocyte differentiation.Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytesSOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling.Detection of genomic signatures of recent selection in commercial broiler chickens.Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.Spatial and temporal regulation of gene expression in the mammalian growth plate.Osteoporosis and atherosclerosis: biological linkages and the emergence of dual-purpose therapies.Myostatin (GDF-8) deficiency increases fracture callus size, Sox-5 expression, and callus bone volume.Bone microstructure and its associated genetic variability in 12 inbred mouse strains: microCT study and in silico genome scan.The Yin and Yang of Sox proteins: Activation and repression in development and diseaseGenome-wide linkage scan for quantitative trait loci underlying normal variation in heel bone ultrasound measures.Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.Sox6, jack of all trades: a versatile regulatory protein in vertebrate developmentTranscriptional control of mesenchymal stem cell differentiation.Unraveling the transcriptional regulatory machinery in chondrogenesis.Regulation of bone and cartilage development by network between BMP signalling and transcription factors.Development and regeneration potential of the mammalian intervertebral disc.Making no bones about it: Transcription factors in vertebrate skeletogenesis and disease.Growth and differentiation of a long bone in limb development, repair and regeneration.Fate of growth plate hypertrophic chondrocytes: death or lineage extension?The osteochondral interface as a gradient tissue: from development to the fabrication of gradient scaffolds for regenerative medicine.ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity.Articular cartilage and joint development from embryogenesis to adulthood.Transcriptional Network Controlling Endochondral Ossification.
P2860
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P2860
Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate
description
2004 nî lūn-bûn
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2004 թուականի Մարտին հրատարակուած գիտական յօդուած
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2004 թվականի մարտին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
Sox5 and Sox6 are needed to de ...... in the cartilage growth plate
@ast
Sox5 and Sox6 are needed to de ...... in the cartilage growth plate
@en
type
label
Sox5 and Sox6 are needed to de ...... in the cartilage growth plate
@ast
Sox5 and Sox6 are needed to de ...... in the cartilage growth plate
@en
prefLabel
Sox5 and Sox6 are needed to de ...... in the cartilage growth plate
@ast
Sox5 and Sox6 are needed to de ...... in the cartilage growth plate
@en
P2093
P2860
P921
P356
P1476
Sox5 and Sox6 are needed to de ...... in the cartilage growth plate
@en
P2093
Patrick Smits
Srijeet Mitra
Véronique Lefebvre
P2860
P304
P356
10.1083/JCB.200312045
P407
P577
2004-03-01T00:00:00Z