Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis. - Wikidata - awgldk - TriplyDB

Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

http://www.wikidata.org/entity/Q33982199

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Translational utility of experimental autoimmune encephalomyelitis: recent developments Regulation of immune responses by prostaglandin E2 Role of prostaglandins in neuroinflammatory and neurodegenerative diseases Prostaglandin E2 and T cells: friends or foes?R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1 Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway.Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression.Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS).At last, a truly selective EP₂ receptor antagonist.The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation Regulation of TH17 cell differentiation by innate immune signals.Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf Manifestations of immune tolerance in the human female reproductive tract.Prostaglandin E2-EP4 signaling persistently amplifies CD40-mediated induction of IL-23 p19 expression through canonical and non-canonical NF-κB pathways.Prostaglandin E₂ promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase.Eicosanoids in metabolic syndrome.G protein-coupled receptors as therapeutic targets for multiple sclerosis.Prostaglandin E2 affects T cell responses through modulation of CD46 expression WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism.Blocking initial infiltration of pioneer CD8(+) T-cells into the CNS via inhibition of SHP-2 ameliorates experimental autoimmune encephalomyelitis in mice.Modulation of dendritic cell function by PGE2 and DHA: a framework for understanding the role of dendritic cells in neuroinflammation.Polyunsaturated Fatty Acid-derived lipid mediators and T cell function.Effect of autoimmunity risk loci on the honeymoon phase in type 1 diabetes.Prostaglandin E2 produced following infection with Theiler's virus promotes the pathogenesis of demyelinating disease.Anemoside A3 ameliorates experimental autoimmune encephalomyelitis by modulating T helper 17 cell response.The role of the prostaglandin E2 receptors in vulnerability of oligodendrocyte precursor cells to death.Prostaglandin E2 EP4 Receptor Activation Attenuates Neuroinflammation and Early Brain Injury Induced by Subarachnoid Hemorrhage in Rats.Statins Reduce Lipopolysaccharide-Induced Cytokine and Inflammatory Mediator Release in an In Vitro Model of Microglial-Like Cells.Chronic administration of EP4-selective agonist exacerbates albuminuria and fibrosis of the kidney in streptozotocin-induced diabetic mice through IL-6.The whipworm (Trichuris suis) secretes prostaglandin E2 to suppress proinflammatory properties in human dendritic cells.Lipoquality control by phospholipase A2 enzymes.Lipoic Acid Stimulates cAMP Production in Healthy Control and Secondary Progressive MS Subjects.mPGES1-Dependent Prostaglandin E2 (PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2 Production.Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1.The toll-like receptor 3 ligand, poly(I:C), improves immunosuppressive function and therapeutic effect of mesenchymal stem cells on sepsis via inhibiting MiR-143.

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

http://www.wikidata.org/entity/Q33982199

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

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Proceedings of the National Academy of Sciences of the United States of America

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

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Chengcan Yao

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Daiji Sakata

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Eri Segi-Nishida

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Kazuhiko Fukuda

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Shuh Narumiya

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Toshiyuki Matsuoka

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Yoshiyasu Esaki

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Youxian Li

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P2860

Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2)

Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis

IL-17 and Th17 Cells

Genetic and pharmacological analysis of prostanoid receptor function

A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs

Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells

Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion

Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

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experimental autoimmune encephalomyelitis

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