Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide.
about
A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesisLipoic acid synthesis: a new family of octanoyltransferases generally annotated as lipoate protein ligasesBluB cannibalizes flavin to form the lower ligand of vitamin B12SPASM and twitch domains in S-adenosylmethionine (SAM) radical enzymesStructures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactionsLipoic acid synthesis and attachment in yeast mitochondria.Role of Nfu1 and Bol3 in iron-sulfur cluster transfer to mitochondrial clients.The suf iron-sulfur cluster synthesis pathway is required for apicoplast maintenance in malaria parasitesDiscovery and characterization of BlsE, a radical S-adenosyl-L-methionine decarboxylase involved in the blasticidin S biosynthetic pathwayDevelopment of quinoxaline 1, 4-dioxides resistance in Escherichia coli and molecular change under resistance selection.Adenosyl radical: reagent and catalyst in enzyme reactions.Biotin and Lipoic Acid: Synthesis, Attachment, and Regulation.Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism.The biosynthesis of thiol- and thioether-containing cofactors and secondary metabolites catalyzed by radical S-adenosylmethionine enzymes.The Streptomyces coelicolor lipoate-protein ligase is a circularly permuted version of the Escherichia coli enzyme composed of discrete interacting domains.Eukaryotic LYR Proteins Interact with Mitochondrial Protein ComplexesMutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes.A radical solution for the biosynthesis of the H-cluster of hydrogenase.Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway.Self-sacrifice in radical S-adenosylmethionine proteins.Crystallographic snapshots of sulfur insertion by lipoyl synthase.The Thermoplasma acidophilum LplA-LplB complex defines a new class of bipartite lipoate-protein ligases.Characterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine.Synergistic effect of reduced polypeptide micelle for co-delivery of doxorubicin and TRAIL against drug-resistance in breast cancer.On the Role of Additional [4Fe-4S] Clusters with a Free Coordination Site in Radical-SAM Enzymes.Structural insights into radical generation by the radical SAM superfamily.Bacterial cysteine desulfurases: versatile key players in biosynthetic pathways of sulfur-containing biofactors.Genome analysis of Chlamydomonas reinhardtii reveals the existence of multiple, compartmentalized iron-sulfur protein assembly machineries of different evolutionary origins.pH-dependent sustained release characteristics of disulfide polymers prepared by simple thermal polymerization.Staphylococcus aureus SufT: an essential iron-sulphur cluster assembly factor in cells experiencing a high-demand for lipoic acid.Evidence for a catalytically and kinetically competent enzyme-substrate cross-linked intermediate in catalysis by lipoyl synthaseReduction of the [2Fe-2S] cluster accompanies formation of the intermediate 9-mercaptodethiobiotin in Escherichia coli biotin synthase.9-Mercaptodethiobiotin is formed as a competent catalytic intermediate by Escherichia coli biotin synthase.9-Mercaptodethiobiotin is generated as a ligand to the [2Fe-2S]+ cluster during the reaction catalyzed by biotin synthase from Escherichia coli.Characterization of RimO, a new member of the methylthiotransferase subclass of the radical SAM superfamilyA combined computational and experimental investigation of the [2Fe-2S] cluster in biotin synthase.Biochemical characterization of the HydE and HydG iron-only hydrogenase maturation enzymes from Thermatoga maritima.Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster.In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters.Improved efficacy of appetite suppression by lipoic acid particles prepared by nanocomminution.
P2860
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P2860
Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Mechanistic investigations of ...... e lipoyl synthase polypeptide.
@ast
Mechanistic investigations of ...... e lipoyl synthase polypeptide.
@en
type
label
Mechanistic investigations of ...... e lipoyl synthase polypeptide.
@ast
Mechanistic investigations of ...... e lipoyl synthase polypeptide.
@en
prefLabel
Mechanistic investigations of ...... e lipoyl synthase polypeptide.
@ast
Mechanistic investigations of ...... e lipoyl synthase polypeptide.
@en
P356
P1476
Mechanistic investigations of ...... e lipoyl synthase polypeptide.
@en
P2093
Robert M Cicchillo
Squire J Booker
P304
P356
10.1021/JA042428U
P407
P577
2005-03-01T00:00:00Z