Contrasting roles for Myc and Mad proteins in cellular growth and differentiation. - Wikidata - awgldk - TriplyDB

Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

http://www.wikidata.org/entity/Q33985770

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Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network The sno gene, which encodes a component of the histone deacetylase complex, acts as a tumor suppressor in mice Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice Modulation of c-myc, max, and mad gene expression during neural differentiation of embryonic stem cells by all-trans-retinoic acid.Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis New Myc-interacting proteins: a second Myc network emerges.Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation.Mad1 function is regulated through elements within the carboxy terminus Targeted deletion of the S-phase-specific Myc antagonist Mad3 sensitizes neuronal and lymphoid cells to radiation-induced apoptosis.Distinct thresholds govern Myc's biological output in vivo.Overexpression of c-MYC promotes an undifferentiated phenotype in cultured astrocytes and allows elevated Ras and Akt signaling to induce gliomas from GFAP-expressing cells in mice.Essential role for Max in early embryonic growth and development c-Myc promotes differentiation of human epidermal stem cells.The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth.Vitamin D receptor as a master regulator of the c-MYC/MXD1 network SIN3-dependent transcriptional repression by interaction with the Mad1 DNA-binding protein Function of the c-Myc antagonist Mad1 during a molecular switch from proliferation to differentiation.Investigation of dmyc Promoter and Regulatory Regions MiR-19a/b modulate the metastasis of gastric cancer cells by targeting the tumour suppressor MXD1.c-Myc/Max heterodimers bind cooperatively to the E-box sequences located in the first intron of the rat ornithine decarboxylase (ODC) gene.Opposite effects of HIF-1α and HIF-2α on the regulation of IL-8 expression in endothelial cells.Oesophageal adenocarcinoma is associated with a deregulation in the MYC/MAX/MAD network.Mad proteins contain a dominant transcription repression domain.Histone deacetylase inhibitor BL1521 induces a G1-phase arrest in neuroblastoma cells through altered expression of cell cycle proteins.Effect of the transcriptional repressor Mad1 on proliferation of human melanoma cells.The expression of the developmentally regulated proto-oncogene Pax-3 is modulated by N-Myc.Mad1 expression in the absence of differentiation: effect of cAMP on the B-lymphoid cell line Reh.MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis.Expression of myc-family, myc-interacting, and myc-target genes during preimplantation mouse development.Expression of c-myc oncoprotein in laryngeal squamous cell carcinoma.

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P2860

Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

http://www.wikidata.org/entity/Q33985770

description

1995 nî lūn-bûn

@nan

1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի օգոստոսին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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name

Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

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Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

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Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

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Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

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Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

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Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

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PNAS.92.18.8488

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Contrasting roles for Myc and Mad proteins in cellular growth and differentiation.

@en

P2093

C Cordon-Cardo

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H W Lee

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I Pellicer

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K Chen

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L Chin

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M Dudast

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N Schreiber-Agus

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R A DePinho

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P2860

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

The ornithine decarboxylase gene is a transcriptional target of c-Myc

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA

Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation.

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