Bcl-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress.
about
Recent advancements of bortezomib in acute lymphocytic leukemia treatmentER stress and apoptosis: a new mechanism for retinal cell death.The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivoABT-737 induces Bim expression via JNK signaling pathway and its effect on the radiation sensitivity of HeLa cellsThe expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large b-cell lymphomaDeficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunctionObatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC- and ABC-DLBCL cells in vitro and in vivoBortezomib for the treatment of non-Hodgkin's lymphomaThe Bruton tyrosine kinase (BTK) inhibitor PCI-32765 synergistically increases proteasome inhibitor activity in diffuse large-B cell lymphoma (DLBCL) and mantle cell lymphoma (MCL) cells sensitive or resistant to bortezomib.AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis.New strategies in diffuse large B-cell lymphoma: translating findings from gene expression analyses into clinical practicePotential usage of proteasome inhibitor bortezomib (Velcade, PS-341) in the treatment of metastatic melanoma: basic and clinical aspectsImplications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-κB and the proteasome.Small molecules as pro-apoptotic anticancer agents.Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.Bortezomib inhibits proteasomal degradation of IκBα and induces mitochondrial dependent apoptosis in activated B-cell diffuse large B-cell lymphoma.Cytotoxicity, drug combinability, and biological correlates of ABT-737 against acute lymphoblastic leukemia cells with MLL rearrangement.The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia.2-deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines.FADD the bad in head and neck cancer.Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors.
P2860
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P2860
Bcl-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Bcl-2 antagonists interact syn ...... on and induction of ER stress.
@ast
Bcl-2 antagonists interact syn ...... on and induction of ER stress.
@en
type
label
Bcl-2 antagonists interact syn ...... on and induction of ER stress.
@ast
Bcl-2 antagonists interact syn ...... on and induction of ER stress.
@en
prefLabel
Bcl-2 antagonists interact syn ...... on and induction of ER stress.
@ast
Bcl-2 antagonists interact syn ...... on and induction of ER stress.
@en
P2093
P2860
P356
P1476
Bcl-2 antagonists interact syn ...... on and induction of ER stress.
@en
P2093
Dmitry Lembersky
Girija Dasmahapatra
Jonathan Friedberg
Lora Kramer
Mohamed Rahmani
Richard I Fisher
Steven Grant
P2860
P304
P356
10.4161/CBT.8.9.8131
P50
P577
2009-05-08T00:00:00Z