about
Of mice, cattle, and humans: the immunology and treatment of river blindnessIL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotypeThe laminated layer: Recent advances and insights into Echinococcus biology and evolutionTissue-resident macrophagesMacrophage proliferation, provenance, and plasticity in macroparasite infectionAnalyzing Airway Inflammation with Chemical Biology: Dissection of Acidic Mammalian Chitinase Function with a Selective Drug-like InhibitorFilarial parasites develop faster and reproduce earlier in response to host immune effectors that determine filarial life expectancyDeletion of parasite immune modulatory sequences combined with immune activating signals enhances vaccine mediated protection against filarial nematodesChitinase 3-like 1 protein levels are elevated in Schistosoma haematobium infected childrenThe secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivoMacrophage activation and polarization: nomenclature and experimental guidelinesInterleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair.Plasmodium chabaudi limits early Nippostrongylus brasiliensis-induced pulmonary immune activation and Th2 polarization in co-infected mice.Vaccination against filarial nematodes with irradiated larvae provides long-term protection against the third larval stage but not against subsequent life cycle stages.Antibody isotype analysis of malaria-nematode co-infection: problems and solutions associated with cross-reactivity.Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cellsThe abundant larval transcript-1 and -2 genes of Brugia malayi encode stage-specific candidate vaccine antigens for filariasisAlternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct.Similarity and diversity in macrophage activation by nematodes, trematodes, and cestodes.Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminthsCandidate innate immune system gene expression in the ecological model Daphnia.Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection.Evolution of Th2 immunity: a rapid repair response to tissue destructive pathogens.Interleukin-5 is essential for vaccine-mediated immunity but not innate resistance to a filarial parasite.Beyond stem cells: self-renewal of differentiated macrophages.Unconventional maturation of dendritic cells induced by particles from the laminated layer of larval Echinococcus granulosusDivergent roles for macrophages in lymphatic filariasis.Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cellsThe biology of nematode- and IL4Rα-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics.Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation.Down Regulation of the TCR Complex CD3ζ-Chain on CD3+ T Cells: A Potential Mechanism for Helminth-Mediated Immune Modulation.Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage.Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulationA dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.Inflammation-induced formation of fat-associated lymphoid clustersAlternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivoTh2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITR ligand costimulation in vivo.Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.Both free-living and parasitic nematodes induce a characteristic Th2 response that is dependent on the presence of intact glycans.
P50
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P50
description
Professor of Immunobiology
@en
wetenschapper
@nl
հետազոտող
@hy
name
Judith Allen
@en
Judith E. Allen
@nl
Judith E. Allen
@sl
Judith Elizabeth Allen
@ast
Judith Elizabeth Allen
@ca
Judith Elizabeth Allen
@de
Judith Elizabeth Allen
@es
Judith Elizabeth Allen
@eu
Judith Elizabeth Allen
@fr
type
label
Judith Allen
@en
Judith E. Allen
@nl
Judith E. Allen
@sl
Judith Elizabeth Allen
@ast
Judith Elizabeth Allen
@ca
Judith Elizabeth Allen
@de
Judith Elizabeth Allen
@es
Judith Elizabeth Allen
@eu
Judith Elizabeth Allen
@fr
altLabel
Judi Allen
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Judith Allen
@en
Judith E. Allen
@ast
Judith E. Allen
@en
Judith E. Allen
@es
Judith Elizabeth Allen
@en
prefLabel
Judith Allen
@en
Judith E. Allen
@nl
Judith E. Allen
@sl
Judith Elizabeth Allen
@ast
Judith Elizabeth Allen
@ca
Judith Elizabeth Allen
@de
Judith Elizabeth Allen
@es
Judith Elizabeth Allen
@eu
Judith Elizabeth Allen
@fr
P166
P1053
C-9198-2011
P106
P1153
7406421497
P166
P21
P31
P3829
P496
0000-0002-3829-066X