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Principles and Overview of Sampling Methods for Modeling Macromolecular Structure and DynamicsA De Novo Protein Binding Pair By Computational Design and Directed EvolutionComputational Design of Proteins Targeting the Conserved Stem Region of Influenza HemagglutininMetal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein HomodimerComputational design of a symmetric homodimer using -strand assemblyComputational design of a protein crystalComputational Design of a Protein-Based Enzyme InhibitorComputational Design of Self-Assembling Protein Nanomaterials with Atomic Level AccuracyAccurate design of co-assembling multi-component protein nanomaterialsMolecular pathways: targeting p21-activated kinase 1 signaling in cancer--opportunities, challenges, and limitationsComputational design of protein-based inhibitors of Plasmodium vivax subtilisin-like 1 proteaseA structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteins3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers.Achievements and Challenges in Computational Protein Design.Engineering a protein-protein interface using a computationally designed libraryIn silico analysis and experimental verification of OSR1 kinase - Peptide interaction.Combined computational design of a zinc-binding site and a protein-protein interaction: one open zinc coordination site was not a robust hotspot for de novo ubiquitin bindingBiochemistry. From computational design to a protein that binds.Anchored design of protein-protein interfaces.RosettaRemodel: a generalized framework for flexible backbone protein design.P21-activated kinase in inflammatory and cardiovascular disease.Therapeutic protein aggregation: mechanisms, design, and control.Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications.Strategies to control the binding mode of de novo designed protein interactions.Restricted sidechain plasticity in the structures of native proteins and complexes.Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5.Scratching the Surface: Resurfacing Proteins to Endow New Properties and Function.An improved Protein G with higher affinity for human/rabbit IgG Fc domains exploiting a computationally designed polar network.Untangling the complexity of PAK1 dynamics: The future challenge.On the binding affinity of macromolecular interactions: daring to ask why proteins interact.Emerging themes in the computational design of novel enzymes and protein-protein interfaces.Integration of cell-free protein coexpression with an enzyme-linked immunosorbent assay enables rapid analysis of protein-protein interactions directly from DNA.A workflow for in silico design of hIL-10 and ebvIL-10 inhibitors using well-known miniprotein scaffolds.Symmetry-Directed Design of Protein Cages and Protein Lattices and Their Applications.AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences.A "fuzzy"-logic language for encoding multiple physical traits in biomolecules.A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds.Creation of artificial protein-protein interactions using α-helices as interfaces.Towards structure-based protein drug design.SDOCK: a global protein-protein docking program using stepwise force-field potentials.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Computational design of a PAK1 binding protein.
@ast
Computational design of a PAK1 binding protein.
@en
type
label
Computational design of a PAK1 binding protein.
@ast
Computational design of a PAK1 binding protein.
@en
prefLabel
Computational design of a PAK1 binding protein.
@ast
Computational design of a PAK1 binding protein.
@en
P2093
P2860
P50
P1476
Computational design of a PAK1 binding protein.
@en
P2093
Glenn L Butterfoss
Ramesh K Jha
Thomas Szyperski
P2860
P304
P356
10.1016/J.JMB.2010.05.006
P407
P577
2010-05-10T00:00:00Z