hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers
about
Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal modelHuman umbilical cord matrix mesenchymal stem cells suppress the growth of breast cancer by expression of tumor suppressor genes.Human Sulfatase-1 Improves the Effectiveness of Cytosine Deaminase Suicide Gene Therapy with 5-Fluorocytosine Treatment on Hepatocellular Carcinoma Cell Line HepG2 In Vitro and In Vivo.The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signalinghSulf-1 inhibits cell proliferation and migration and promotes apoptosis by suppressing stat3 signaling in hepatocellular carcinoma.Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use.HSULF-1 inhibits ERK and AKT signaling and decreases cell viability in vitro in human lung epithelial cells.An oncolytic adenovirus regulated by a radiation-inducible promoter selectively mediates hSulf-1 gene expression and mutually reinforces antitumor activity of I131-metuximab in hepatocellular carcinoma.Human sulfatase-1 inhibits the migration and proliferation of SMMC-7721 hepatocellular carcinoma cells by downregulating the growth factor signaling.The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4.
P2860
Q34104125-4704155B-BB36-4A38-B112-D95C8D9D7684Q35571688-8E7FAA65-75A7-4128-BEE7-024EA257A78CQ36794502-27256836-6FAA-4D71-8582-804857BAC6CBQ37467900-5B07F93E-00F2-4987-9D25-B9E982CF2001Q37652618-403294EF-4C6D-4BB9-A573-17B2BAC5C689Q38418286-327A7B62-01B1-42C9-88BE-320350B3FDEBQ39300738-2DEAD22F-FB2F-4197-875A-95C0EE33D798Q41134603-A2AB14B1-5DCF-46BC-92BA-2DE40C7EA4EAQ45190761-87469FCA-B818-4F77-B731-7FD392A9C61CQ51033843-734DC090-C260-4D18-A307-A5C18520B2A3
P2860
hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers
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2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
hSulf-1 gene exhibits anticanc ...... R-2 signaling in human cancers
@ast
hSulf-1 gene exhibits anticanc ...... R-2 signaling in human cancers
@en
type
label
hSulf-1 gene exhibits anticanc ...... R-2 signaling in human cancers
@ast
hSulf-1 gene exhibits anticanc ...... R-2 signaling in human cancers
@en
prefLabel
hSulf-1 gene exhibits anticanc ...... R-2 signaling in human cancers
@ast
hSulf-1 gene exhibits anticanc ...... R-2 signaling in human cancers
@en
P2093
P2860
P1433
P1476
hSulf-1 gene exhibits anticanc ...... R-2 signaling in human cancers
@en
P2093
Changqing Su
Duanming Wang
Haihua Qian
Jiahe Yang
Mengchao Wu
Qijun Qian
Weifeng Tan
P2860
P304
P356
10.1371/JOURNAL.PONE.0023274
P407
P577
2011-08-10T00:00:00Z