Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat - Wikidata - awgldk - TriplyDB

Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat

Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat

http://www.wikidata.org/entity/Q33997420

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Evaluating the role of atazanavir/cobicistat and darunavir/cobicistat fixed-dose combinations for the treatment of HIV-1 infection Clinical use of cobicistat as a pharmacoenhancer of human immunodeficiency virus therapy Clinical effectiveness of dolutegravir in the treatment of HIV/AIDS The role of drug transporters in the kidney: lessons from tenofovir Once-Daily, Single-Tablet Regimens For the Treatment of HIV-1 Infection Sex-differences in renal expression of selected transporters and transcription factors in lean and obese Zucker spontaneously hypertensive fatty rats A pharmacogenetic candidate gene study of tenofovir-associated Fanconi syndrome.Protease Inhibitors and Renal Function in Patients with HIV Infection: a Systematic Review.Telaprevir and ribavirin interaction: higher ribavirin levels are not only due to renal dysfunction during triple therapy.Global Metabolomic Identification of Long-Term Dose-Dependent Urinary Biomarkers in Nonhuman Primates Exposed to Ionizing Radiation.Organic anion transporter 2 transcript variant 1 shows broad ligand selectivity when expressed in multiple cell lines.Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters.What do drug transporters really do?The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin.Estimated Glomerular Filtration Rate Trajectories in HIV-Infected Subjects Treated With Different Ritonavir-Boosted Protease Inhibitors and Tenofovir Disoproxil Fumarate or Abacavir.The Effect of Dolutegravir on the Pharmacokinetics of Metformin in Healthy Subjects.Dolutegravir: a review of its use in the management of HIV-1 infection in adolescents and adults.Darunavir/cobicistat once daily for the treatment of HIV.Cadmium or cadmium compounds and chronic kidney disease in workers and the general population: a systematic review.The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?Serum creatinine and cystatin C provide conflicting evidence of acute kidney injury following acute ingestion of potassium permanganate and oxalic acid.In Vitro and In Vivo Interaction Studies Between Lesinurad, a Selective Urate Reabsorption Inhibitor, and Major Liver or Kidney Transporters.Evaluation of Serum Creatinine Changes With Integrase Inhibitor Use in Human Immunodeficiency Virus-1 Infected Adults.Structure and function of multidrug and toxin extrusion proteins (MATEs) and their relevance to drug therapy and personalized medicine.Renal effects of novel antiretroviral drugs.Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1.Evaluation and Quantitative Prediction of Renal Transporter-Mediated Drug-Drug Interactions.Renal Drug Transporters and Drug Interactions.Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics.Kidney Disease in HIV: Moving beyond HIV-Associated Nephropathy.Impact of early versus deferred antiretroviral therapy on estimated glomerular filtration rate in HIV-positive individuals in the START trial.Atazanavir sulfate + cobicistat for the treatment of HIV infection.Administration of tenofovir disoproxil fumarate-based antiretroviral therapy in an HIV-infected patient following unilateral nephrectomy.Effects of Antiretroviral Therapy on Immune Function and Arterial Inflammation in Treatment-Naive Patients With Human Immunodeficiency Virus Infection.Serum creatinine elevation after switch to dolutegravir in a human immunodeficiency virus-positive kidney transplant recipient.Cobicistat versus ritonavir boosting and differences in the drug-drug interaction profiles with co-medications.Drug interaction profile of the HIV integrase inhibitor cabotegravir: assessment from in vitro studies and a clinical investigation with midazolam.Overdose of dolutegravir in combination with tenofovir disaproxil fumarate/emtricitabine in suicide attempt in a 21-year old patient.IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats.N(1)-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction.

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Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat

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2014 nî lūn-bûn

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Yong Huang

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P2860

Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3 trial, analysis of results after 48 weeks

Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

A rise in plasma creatinine that is not a sign of renal failure: which drugs can be responsible?

Creatinine elevation in patients receiving amiodarone correlates with serum amiodarone concentration

Effects of moderate-dose versus high-dose trimethoprim on serum creatinine and creatinine clearance and adverse reactions.

Major contribution of tubular secretion to creatinine clearance in mice.

DEPRESSION OF THE EXOGENOUS CREATININE/INULIN OR THIOSULFATE CLEARANCE RATIOS IN MAN BY DIODRAST AND p-AMINOHIPPURIC ACID.

Proximal tubular secretion of creatinine by organic cation transporter OCT2 in cancer patients.

Pyrimethamine inhibits renal secretion of creatinine

Lack of effect of DX-619, a novel des-fluoro(6)-quinolone, on glomerular filtration rate measured by serum clearance of cold iohexol.

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