The role of autophagy in alpha-1-antitrypsin deficiency: a specific cellular response in genetic diseases associated with aggregation-prone proteins.
about
One step at a time: endoplasmic reticulum-associated degradationC. elegans in high-throughput drug discoveryAutophagy in the Pathogenesis of DiseaseFBG1 Is the Final Arbitrator of A1AT-Z DegradationNew Concepts in Alpha-1 Antitrypsin Deficiency Disease Mechanisms.Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LS substrates.Molecular chaperones and substrate ubiquitination control the efficiency of endoplasmic reticulum-associated degradation.Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytesRole of autophagy in liver physiology and pathophysiology.Z α-1 antitrypsin deficiency and the endoplasmic reticulum stress response.Combination therapy utilizing shRNA knockdown and an optimized resistant transgene for rescue of diseases caused by misfolded proteins.Role of Carbonyl Modifications on Aging-Associated Protein Aggregation.Hydrodynamic size-based separation and characterization of protein aggregates from total cell lysates.Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy.Autophagy and ethanol-induced liver injury.Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic beta-cells.Autophagy: regulation and role in disease.Autophagy in hepatic fibrosis.MicroRNA regulation of autophagy in cardiovascular disease.Hepatic fibrosis and carcinogenesis in α1-antitrypsin deficiency: a prototype for chronic tissue damage in gain-of-function disorders.Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis.The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and α-1 anti-trypsin deficiency.Pore formation by human stefin B in its native and oligomeric states and the consequent amyloid induced toxicity.Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation.Visualization of reticulophagy in living cells using an endoplasmic reticulum-targeted p62 mutant.Expression of autophagy-associated proteins in papillary thyroid carcinoma.Dysfunctional glycogen storage in a mouse model of alpha1-antitrypsin deficiency.A new autophagy-related checkpoint in the degradation of an ERAD-M target.Engineering of chaperone systems and of the unfolded protein response.Alpha-1 Antitrypsin-Deficient Macrophages Have Increased Matriptase-Mediated Proteolytic Activity.Regulator of G Signaling 16 is a marker for the distinct endoplasmic reticulum stress state associated with aggregated mutant alpha1-antitrypsin Z in the classical form of alpha1-antitrypsin deficiency.Decreased expression of Beclin-1 and LC3 in human lung cancer.Cytotoxicity of Aberrant Proteins
P2860
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P2860
The role of autophagy in alpha-1-antitrypsin deficiency: a specific cellular response in genetic diseases associated with aggregation-prone proteins.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The role of autophagy in alpha ...... th aggregation-prone proteins.
@ast
The role of autophagy in alpha ...... th aggregation-prone proteins.
@en
type
label
The role of autophagy in alpha ...... th aggregation-prone proteins.
@ast
The role of autophagy in alpha ...... th aggregation-prone proteins.
@en
prefLabel
The role of autophagy in alpha ...... th aggregation-prone proteins.
@ast
The role of autophagy in alpha ...... th aggregation-prone proteins.
@en
P356
P1433
P1476
The role of autophagy in alpha ...... th aggregation-prone proteins.
@en
P2093
David H Perlmutter
P304
P356
10.4161/AUTO.2882
P577
2006-10-05T00:00:00Z