Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
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Exome sequencing identifies recurrent somatic RAC1 mutations in melanomaGenetics of melanocytic neviKita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafishClonal architectures and driver mutations in metastatic melanomasThe incidence and position of melanocytic nevi for the purposes of forensic image comparison.RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.Molecular pathogenesis of sporadic melanoma and melanoma-initiating cells.Biologically distinct subsets of neviMelanoma in congenital melanocytic naevi.Melanoma: clinical features and genomic insights.Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.Oncogenic codon 13 NRAS mutation in a primary mesenchymal brain neoplasm and nevus of a child with neurocutaneous melanosis.Rapidly lethal metastatic melanoma arising from a large congenital melanocytic naevus.Targeted therapy for melanoma: a primer.Genotyping of cutaneous melanoma.A high-content screening assay for small-molecule modulators of oncogene-induced senescence.Melanoma genotypes and phenotypes get personal.EZH2-dependent suppression of a cellular senescence phenotype in melanoma cells by inhibition of p21/CDKN1A expression.Update on Molecular Pathology of Cutaneous Melanocytic Lesions: What is New in Diagnosis and Molecular Testing for Treatment?A melanoma subtype: uveal melanoma.BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site.Agminated segmental nevi demonstrating intranevic concordance of BRAF statusThe emerging role of the thrombin receptor (PAR-1) in melanoma metastasis--a possible therapeutic target.A murine model for the development of melanocytic nevi and their progression to melanoma.NRAS(Q61K) mutated primary leptomeningeal melanoma in a child: case presentation and discussion on clinical and diagnostic implicationsAbsence of senescence-associated beta-galactosidase activity in human melanocytic nevi in vivo.Human giant congenital melanocytic nevus exhibits potential proteomic alterations leading to melanotumorigenesis.Coexpression of SOX10/CD271 (p75(NTR)) and β-Galactosidase in Large to Giant Congenital Melanocytic Nevi of Pediatric Patients.The dysplastic nevus: from historical perspective to management in the modern era: part II. Molecular aspects and clinical management.Genomic aberrations in spitzoid melanocytic tumours and their implications for diagnosis, prognosis and therapyAssessing cell and organ senescence biomarkersThe molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia.Atypical melanocytic proliferations and new primary melanomas in patients with advanced melanoma undergoing selective BRAF inhibitionMultiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRASBRAF(E600) in benign and malignant human tumours.A dual concept of nevogenesis: theoretical considerations based on dermoscopic features of melanocytic nevi.Growth factors and oncogenes as targets in melanoma: lost in translation?BRAF kinase in melanoma development and progression.The Conundrum of Genetic "Drivers" in Benign Conditions.Molecular markers of tumor progression in melanoma.
P2860
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P2860
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
@ast
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
@en
type
label
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
@ast
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
@en
prefLabel
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
@ast
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
@en
P2093
P356
P1476
Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.
@en
P2093
Boris C Bastian
Dan Pinkel
Jürgen Bauer
P2888
P304
P356
10.1038/SJ.JID.5700490
P407
P577
2006-08-03T00:00:00Z
P5875
P6179
1013768299