The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia
about
Intranasal immunization with killed unencapsulated whole cells prevents colonization and invasive disease by capsulated pneumococciCholine Binding Proteins from Streptococcus pneumoniae: A Dual Role as Enzybiotics and Targets for the Design of New AntimicrobialsStructural determinants of host specificity of complement Factor H recruitment by Streptococcus pneumoniaeThe host immune dynamics of pneumococcal colonization: implications for novel vaccine developmentDominant role of nucleotide substitution in the diversification of serotype 3 pneumococci over decades and during a single infectionAdhesion and invasion of Streptococcus pneumoniae to primary and secondary respiratory epithelial cellsEpitope mapping of a protective monoclonal antibody against Pneumocystis carinii with shared reactivity to Streptococcus pneumoniae surface antigen PspACrystallization and preliminary X-ray diffraction studies of the pneumococcal teichoic acid phosphorylcholine esterase Pce.Differential activation of inflammatory pathways in A549 type II pneumocytes by Streptococcus pneumoniae strains with different adherence properties.Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodiesLysozyme M deficiency leads to an increased susceptibility to Streptococcus pneumoniae-induced otitis mediaHelper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.Diversity of PspA: mosaic genes and evidence for past recombination in Streptococcus pneumoniae.Immunogenicity of a live recombinant Salmonella enterica serovar typhimurium vaccine expressing pspA in neonates and infant mice born from naive and immunized mothersImmunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection.Differential PsaA-, PspA-, PspC-, and PdB-specific immune responses in a mouse model of pneumococcal carriage.Identification of the targets of cross-reactive antibodies induced by Streptococcus pneumoniae colonization.Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal cloneMapping of epitopes recognized by antibodies induced by immunization of mice with PspA and PspC.The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysinIntranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae.Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae.Characterization of binding of human lactoferrin to pneumococcal surface protein ARequirement for capsule in colonization by Streptococcus pneumoniae.Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA.Detection of large numbers of pneumococcal virulence genes in streptococci of the mitis group.Contributions to protection from Streptococcus pneumoniae infection using the monovalent recombinant protein vaccine candidates PcpA, PhtD, and PlyD1 in an infant murine model during challengeRole of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniaeThe human complement regulator factor H binds pneumococcal surface protein PspC via short consensus repeats 13 to 15.Development of Streptococcus pneumoniae Vaccines Using Live VectorsPrevalence and clonal distribution of pcpA, psrP and Pilus-1 among pediatric isolates of Streptococcus pneumoniae.Preclinical evaluation of the Pht proteins as potential cross-protective pneumococcal vaccine antigens.Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniaeHuman antibodies to PhtD, PcpA, and Ply reduce adherence to human lung epithelial cells and murine nasopharyngeal colonization by Streptococcus pneumoniae.Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection modelEvaluation of a vaccine formulation against Streptococcus pneumoniae based on choline-binding proteins.The contribution of PspC to pneumococcal virulence varies between strains and is accomplished by both complement evasion and complement-independent mechanismsRelative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniaeMosaicism in the alpha-like protein genes of group B streptococciDifferential role of CbpA and PspA in modulation of in vitro CXC chemokine responses of respiratory epithelial cells to infection with Streptococcus pneumoniae.
P2860
Q24548662-BB9DA177-AD7B-4836-A5FD-5904F12D75E7Q26744448-7814122E-3986-4843-A2D0-2F7C28962E3CQ27695722-A69A392A-E1FE-4494-921E-879FF57E01C0Q28084920-0BCC8970-9128-435C-A228-2049D7A0293EQ28534306-9E5E4E6D-F18C-41F7-B9F7-8E6D8F1B2532Q29247863-1E2D1D71-692A-4A4D-9FC3-31B1B519E698Q33198525-EC174D15-AB2D-4CF3-9760-2A3C0BAE263DQ33235194-4A225095-E2A6-4B8D-8B4D-CE6777CD7AE9Q33239521-CFE0559B-6E38-42A4-919F-D902822683FFQ33312893-D0AB2522-CCC4-44DD-97E6-C842FC39E16FQ33374661-1E60D666-A4D4-4228-BF43-66B346014549Q33535951-3FDD15D2-EF47-4DD3-8A7C-AD96BECE0B2FQ33592652-972D19AD-C731-4D91-83D7-F0CA67C56334Q33725174-F9246AD9-613A-49BC-ACD3-B75AE5BC1FC5Q33725192-AC4D64C1-002B-4BBD-91E7-FC25D5D25C53Q33798317-322C7755-04CD-47C5-86E0-DE7B5A0D882BQ33826031-CD42C25F-8575-4184-8370-1D7B630DB24EQ33891667-3071BFA1-C88B-42C2-9761-B0143CE17FE8Q33899358-D2BCC334-F2DD-45C4-8A7A-DE60C45A35EDQ33996189-0BBB511C-D49F-4414-9BC3-18AE996501C6Q34003306-155E29C6-9B6C-418B-B7EB-95DD3C58408DQ34004489-8886688B-3787-41F0-8875-D65843C09C00Q34007403-7F0A823B-F7CA-4053-AE45-B23FB0C00D88Q34007742-BAC400F5-DA81-49A9-A4C8-FE42BE32B791Q34009174-B392CD87-CBF0-4913-A4FC-0F61CB36E59DQ34046452-4C0CA5BB-A576-46BE-8DDD-AD61BF34C8ABQ34057765-4FC26840-26B8-413E-B9C0-596F12345BF7Q34121334-8F1B84AA-15A3-407E-96A5-BBE419691884Q34132121-5AA83C24-2F7C-44BF-BA00-364FD5A9AC47Q34316015-6A3396CB-1321-4D27-9840-580FD92249B6Q34358647-476B85EE-7A38-4951-8953-D7A288844E3BQ34484575-27343BBF-BB5F-4554-91F1-09B3C5628594Q34530684-036E053B-D816-46CB-BF04-2678D8BC594EQ34595710-BFAE183A-4078-41D9-83D3-BD8B55481655Q34713678-3254C29D-CF7E-4280-9ED8-A94338D9F669Q35021099-9AE30FBD-5AAA-49FF-93A3-83BBA6373B3DQ35073802-97388584-9723-44F2-B8B0-FED9E3F51841Q35165275-F1D2FA6D-9B08-46AF-94EE-AB5C760FF848Q35210922-C31F33D7-7A4F-451B-803C-1E7B81E5D518Q35220280-974BF177-4480-4F4B-965A-E4770BAFD51D
P2860
The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@ast
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@en
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@nl
type
label
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@ast
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@en
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@nl
prefLabel
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@ast
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@en
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@nl
P2093
P2860
P1476
The pspC gene of Streptococcus ...... ity to pneumococcal bacteremia
@en
P2093
A Brooks-Walter
D E Briles
S K Hollingshead
P2860
P304
P407
P577
1999-12-01T00:00:00Z