Requirement of non-T cells that produce gamma interferon for prevention of reactivation of Toxoplasma gondii infection in the brain
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Immune response and immunopathology during toxoplasmosisEffects of Toxoplasma gondii infection on the brainInterferon-gamma- and perforin-mediated immune responses for resistance against Toxoplasma gondii in the brainRemoval of Toxoplasma gondii cysts from the brain by perforin-mediated activity of CD8+ T cells.Behavior of Neutrophil Granulocytes during Toxoplasma gondii Infection in the Central Nervous System.VCAM-1/α4β1 integrin interaction is crucial for prompt recruitment of immune T cells into the brain during the early stage of reactivation of chronic infection with Toxoplasma gondii to prevent toxoplasmic encephalitis.CD8(+)-T-cell immunity against Toxoplasma gondii can be induced but not maintained in mice lacking conventional CD4(+) T cellsPredominant interferon-γ-mediated expression of CXCL9, CXCL10, and CCL5 proteins in the brain during chronic infection with Toxoplasma gondii in BALB/c mice resistant to development of toxoplasmic encephalitis.Toxoplasma IgG and IgA, but not IgM, antibody titers increase in sera of immunocompetent mice in association with proliferation of tachyzoites in the brain during the chronic stage of infectionHost resistance in the brain against Toxoplasma gondii.CXCL9 is important for recruiting immune T cells into the brain and inducing an accumulation of the T cells to the areas of tachyzoite proliferation to prevent reactivation of chronic cerebral infection with Toxoplasma gondii.CD8 T Cells and Toxoplasma gondii: A New ParadigmEvidence for finely-regulated asynchronous growth of Toxoplasma gondii cysts based on data-driven model selection.Cutting Edge: IFN-γ Produced by Brain-Resident Cells Is Crucial To Control Cerebral Infection with Toxoplasma gondii.Toxoplasma gondii antigens recognized by IgG antibodies differ between mice with and without active proliferation of tachyzoites in the brain during the chronic stage of infection.Gamma interferon production, but not perforin-mediated cytolytic activity, of T cells is required for prevention of toxoplasmic encephalitis in BALB/c mice genetically resistant to the disease.IL-2 produced by CD8+ immune T cells can augment their IFN-γ production independently from their proliferation in the secondary response to an intracellular pathogen.CD8(+) T cells remove cysts of Toxoplasma gondii from the brain mostly by recognizing epitopes commonly expressed by or cross-reactive between type II and type III strains of the parasiteTranscriptome analysis of mouse brain infected with Toxoplasma gondii.Modulating effect of Allium cepa on kidney apoptosis caused by Toxoplasma gondii.Complex immune cell interplay in the gamma interferon response during Toxoplasma gondii infectionToxoplasma gondii prevents neuron degeneration by interferon-gamma-activated microglia in a mechanism involving inhibition of inducible nitric oxide synthase and transforming growth factor-beta1 production by infected microglia.Soluble factors released by Toxoplasma gondii-infected astrocytes down-modulate nitric oxide production by gamma interferon-activated microglia and prevent neuronal degeneration.Determination of a Key Antigen for Immunological Intervention To Target the Latent Stage of Toxoplasma gondii.Infection of immunodeficient horses with Sarcocystis neurona does not result in neurologic disease.Evaluation of the effects of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-gamma knockout mice using QC-PCR.Pathogenicity of Toxoplasma gondii through B-2 cell-mediated downregulation of host defense responses.Inducible nitric oxide synthase in innate immune cells is important for restricting cyst formation of Toxoplasma gondii in the brain but not required for the protective immune process to remove the cysts.PD-L1, TIM-3, and CTLA-4 blockade fail to promote resistance to secondary infection with virulent strains of
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P2860
Requirement of non-T cells that produce gamma interferon for prevention of reactivation of Toxoplasma gondii infection in the brain
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2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
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2001年论文
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name
Requirement of non-T cells tha ...... gondii infection in the brain
@ast
Requirement of non-T cells tha ...... gondii infection in the brain
@en
Requirement of non-T cells tha ...... gondii infection in the brain
@nl
type
label
Requirement of non-T cells tha ...... gondii infection in the brain
@ast
Requirement of non-T cells tha ...... gondii infection in the brain
@en
Requirement of non-T cells tha ...... gondii infection in the brain
@nl
prefLabel
Requirement of non-T cells tha ...... gondii infection in the brain
@ast
Requirement of non-T cells tha ...... gondii infection in the brain
@en
Requirement of non-T cells tha ...... gondii infection in the brain
@nl
P2860
P1476
Requirement of non-T cells tha ...... gondii infection in the brain
@en
P2860
P304
P356
10.1128/IAI.69.5.2920-2927.2001
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P577
2001-05-01T00:00:00Z