Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis. - Wikidata - awgldk - TriplyDB

Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis.

Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis.

http://www.wikidata.org/entity/Q34008645

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Depolarization Controls TRAIL-Sensitization and Tumor-Selective Killing of Cancer Cells: Crosstalk with ROS Cytotoxicity of dietary flavonoids on different human cancer types Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish Wogonin induces Beclin-1/PI3K and reactive oxygen species-mediated autophagy in human pancreatic cancer cells Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263.NSAIDs, Mitochondria and Calcium Signaling: Special Focus on Aspirin/Salicylates Combination of wogonin and sorafenib effectively kills human hepatocellular carcinoma cells through apoptosis potentiation and autophagy inhibition Wogonin attenuates ovalbumin antigen-induced neutrophilic airway inflammation by inhibiting th17 differentiation.Use of isoform-specific UGT metabolism to determine and describe rates and profiles of glucuronidation of wogonin and oroxylin A by human liver and intestinal microsomes.Proteome profiling of lipopolysaccharide induced L6 rat skeletal muscle cells response to flavonoids from Scutellaria baicalensis Georgi.Synergistic inhibitory effect of wogonin and low-dose paclitaxel on gastric cancer cells and tumor xenografts Anti-cancer natural products isolated from chinese medicinal herbs Chemical compositions and antiproliferation activities of the chloroform fraction from Pyropolyporus fomentarius in K562 cells.Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.Wogonoside induces apoptosis in Bel-7402, a hepatocellular carcinoma cell line, by regulating Bax/Bcl-2.Wogonin induces reactive oxygen species production and cell apoptosis in human glioma cancer cells.Wogonin inhibits the proliferation of myelodysplastic syndrome cells through the induction of cell cycle arrest and apoptosis.A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis.Wogonin inhibits multiple myeloma-stimulated angiogenesis via c-Myc/VHL/HIF-1α signaling axis.Dimethyl fumarate restores apoptosis sensitivity and inhibits tumor growth and metastasis in CTCL by targeting NF-κB.Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid.Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205.Cancer Prevention and Therapy: Integrating Traditional Korean Medicine Into Modern Cancer Care.Natural products against hematological malignancies and identification of their targets.Application of a new method, orthogonal projection to latent structure (OPLS) combined with principal component analysis (PCA), to screening of prostaglandin E2 production inhibitory flavonoids in Scutellaria Root.Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1.Tax contributes apoptosis resistance to HTLV-1-infected T cells via suppression of Bid and Bim expression.Licochalcone A induces apoptosis through endoplasmic reticulum stress via a phospholipase Cγ1-, Ca(2+)-, and reactive oxygen species-dependent pathway in HepG2 human hepatocellular carcinoma cells.Wogonin ameliorates lipotoxicity-induced apoptosis of cultured vascular smooth muscle cells via interfering with DAG-PKC pathway.Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells.Bezielle (BZL101)-induced oxidative stress damage followed by redistribution of metabolic fluxes in breast cancer cells: a combined proteomic and metabolomic study.Antitumor activity of erythromycin on human neuroblastoma cell line (SH-SY5Y).Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis.Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63.Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells.Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects.An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells.Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin.PLSCR1/IP3R1/Ca2+ axis contributes to differentiation of primary AML cells induced by wogonoside.Delayed growth of glioma by Scutellaria flavonoids involve inhibition of Akt, GSK-3 and NF-κB signaling.

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P2860

Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis.

http://www.wikidata.org/entity/Q34008645

description

2007 nî lūn-bûn

@nan

2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

@ast

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

@en

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

@nl

type

label

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

@ast

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

@en

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

@nl

prefLabel

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

@ast

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

@en

Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

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Wogonin preferentially kills m ...... and Ca2+-dependent apoptosis.

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Anette Merling

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Karsten Gülow

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Lutz Edler

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Marco Giaisi

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Min Li-Weber

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Peter H Krammer

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Stefanie C Fas

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Sven Baumann

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Wolfgang W Müller

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2354-2363

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scholarly article

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10.1182/BLOOD-2007-06-096198

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4

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111

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18070986

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