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Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promotersRelease, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD⁺) in the rat brainThe purinergic neurotransmitter revisited: a single substance or multiple players?The role of mammalian sirtuins in the regulation of metabolism, aging, and longevityA rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degenerationNAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal deathQuinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection.Decreased SIRT2 activity leads to altered microtubule dynamics in oxidatively-stressed neuronal cells: implications for Parkinson's disease.Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration.Depletion of the central metabolite NAD leads to oncosis-mediated cell death.Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in miceDependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618How to live long and prosper: autophagy, mitochondria, and aging.Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models.Autophagy: regulation and role in disease.Metabolism, compartmentation, transport and production of acetate in the cortical brain tissue slice.The human NAD metabolome: Functions, metabolism and compartmentalization.Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is a tumoural cytokine released from melanoma.A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling.Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells.Hypoxia causes autophagic stress and derangement of metabolic adaptation in a cell model of amyotrophic lateral sclerosis.Ca(2+) signaling occurs via second messenger release from intraorganelle synthesis sites.Emerging Potential Benefits of Modulating NAD+ Metabolism in Cardiovascular Disease.Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Characterization of NAD uptake in mammalian cells.
@ast
Characterization of NAD uptake in mammalian cells.
@en
Characterization of NAD uptake in mammalian cells.
@nl
type
label
Characterization of NAD uptake in mammalian cells.
@ast
Characterization of NAD uptake in mammalian cells.
@en
Characterization of NAD uptake in mammalian cells.
@nl
prefLabel
Characterization of NAD uptake in mammalian cells.
@ast
Characterization of NAD uptake in mammalian cells.
@en
Characterization of NAD uptake in mammalian cells.
@nl
P2093
P2860
P50
P356
P1476
Characterization of NAD uptake in mammalian cells.
@en
P2093
Ambra A Grolla
Cintia Blasi Roman
Cristina Travelli
Emanuela Ercolano
Pier Luigi Canonico
Ubaldina Galli
P2860
P304
P356
10.1074/JBC.M706204200
P407
P577
2008-01-07T00:00:00Z