Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. - Wikidata - awgldk - TriplyDB

Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy.

Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy.

http://www.wikidata.org/entity/Q34009569

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Interventions to prevent steroid-induced osteoporosis and osteoporotic fractures in Duchenne muscular dystrophy Impact of Dental Implant Surface Modifications on Osseointegration Position Statement: Drug Holiday in Osteoporosis Treatment with Bisphosphonates in South Korea Medication Related Osteonecrosis of the Jaw: 2015 Position Statement of the Korean Society for Bone and Mineral Research and the Korean Association of Oral and Maxillofacial Surgeons Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research Oral bisphosphonates and colon cancer: an update Bisphosphonate Related Osteonecrosis of the Jaw: An Update Postmenopausal osteoporosis treatment with antiresorptives: effects of discontinuation or long-term continuation on bone turnover and fracture risk--a perspective Updates on mechanism of action and clinical efficacy of risedronate in osteoporosis Managing osteoporosis in ulcerative colitis: something new?Bisphosphonate drug holiday: choosing appropriate candidates Denosumab: mechanism of action and clinical outcomes Exposure to bisphosphonates and risk of colorectal cancer Dental complications and management of patients on bisphosphonate therapy: A review article Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding Increasing options for the treatment of osteoporosis Controlled delivery of zoledronate improved bone formation locally in vivo Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells Alterations of mass density and 3D osteocyte lacunar properties in bisphosphonate-related osteonecrotic human jaw bone, a synchrotron µCT study.Treatment of bone marrow lesions (bone marrow edema).The effect of medications which cause inflammation of the gastro-oesophageal tract on cancer risk: a nested case-control study of routine Scottish data.Early responsiveness of women with osteoporosis to teriparatide after therapy with alendronate or risedronate Association between alendronate and atypical femur fractures: a meta-analysis.Bisphosphonates and bone quality.Bisphosphonates for treatment of osteoporosis: expected benefits, potential harms, and drug holidays.Longitudinal Change in Trabecular Bone Score during and after Treatment of Osteoporosis in Postmenopausal Korean Women Direct antitumour activity of zoledronic acid: preclinical and clinical data.Novel Radiolabeled Bisphosphonates for PET Diagnosis and Endoradiotherapy of Bone Metastases Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs.The effect of antiresorptives on bone quality.Morphological assessment of basic multicellular unit resorption parameters in dogs shows additional mechanisms of bisphosphonate effects on bone.Isoprenoids, small GTPases and Alzheimer's disease.Risedronate's efficacy: from randomized clinical trials to real clinical practice.Strontium ranelate and alendronate have differing effects on distal tibia bone microstructure in women with osteoporosis Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis.Update on estrogens and the skeleton An NMR metabolomic study on the effect of alendronate in ovariectomized mice.The role of zoledronic acid in the adjuvant treatment of breast cancer: current perspectives.Effect of local zoledronate on implant osseointegration in a rat model Increase in the serum parathyroid hormone level during a bisphosphonate drug holiday.

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P2860

Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy.

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Mechanisms of action of bispho ...... influence on clinical efficacy

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P2860

Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding

Bisphosphonates: from bench to bedside

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

Ibandronate in osteoporosis: preclinical data and rationale for intermittent dosing.

Using real-world data for coverage and payment decisions: the ISPOR Real-World Data Task Force report.

Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group.

Manipulation of the anabolic and catabolic responses with OP-1 and zoledronic acid in a rat critical defect model.

The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates.

Bisphosphonates act on rat bone resorption through the mediation of osteoblasts.

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