Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies.
about
7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activityDrug absorption efficiency in Caenorhbditis elegans delivered by different methodsSynthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.A fluorescent HTS assay for phosphohydrolases based on nucleoside 5'-fluorophosphates: its application in screening for inhibitors of mRNA decapping scavenger and PDE-I.Synthesis and evaluation of fluorescent cap analogues for mRNA labelling.mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translationAnalysis of decapping scavenger cap complex using modified cap analogs reveals molecular determinants for efficient cap binding.
P2860
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P2860
Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@ast
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@en
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@nl
type
label
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@ast
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@en
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@nl
prefLabel
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@ast
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@en
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@nl
P2093
P2860
P1433
P1476
Structural requirements for Ca ...... d HPLC enzyme kinetic studies.
@en
P2093
Anna Wypijewska
Elzbieta Bojarska
Janusz Stepinski
Marzena Jankowska-Anyszka
Richard E Davis
P2860
P304
P356
10.1111/J.1742-4658.2010.07709.X
P407
P577
2010-06-08T00:00:00Z