Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression.

Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression.

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http://www.wikidata.org/entity/Q34017088
The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expressionRocaglamide breaks TRAIL resistance in HTLV-1-associated adult T-cell leukemia/lymphoma by translational suppression of c-FLIP expression.Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity.Chemistry and biology of rocaglamides (= flavaglines) and related derivatives from aglaia species (meliaceae)Total synthesis of (±)-rocaglamide via oxidation-initiated Nazarov cyclization.Chinese herb derived-Rocaglamide A is a potent inhibitor of pancreatic cancer cells.Overcoming resistance to TRAIL-induced apoptosis in solid tumor cells by simultaneously targeting death receptors, c-FLIP and IAPs.Flavaglines: potent anticancer drugs that target prohibitins and the helicase eIF4A.Molecular mechanisms and anti-cancer aspects of the medicinal phytochemicals rocaglamides (=flavaglines).Rocaglamide-A Potentiates Osteoblast Differentiation by Inhibiting NF-κB Signaling.The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints.The Wilms' tumor suppressor WT1 enhances CD95L expression and promotes activation-induced cell death in leukemic T cells.Rocaglamide and a XIAP inhibitor cooperatively sensitize TRAIL-mediated apoptosis in Hodgkin's lymphomas.
P2860

Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression.

Item
http://www.wikidata.org/entity/Q34017088
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@ast
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@en
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@nl
type
label
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@ast
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@en
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@nl
prefLabel
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@ast
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@en
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@nl
P1433
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P2093
P2860
P2888
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P1476
Rocaglamide sensitizes leukemi ...... f CD95L and c-FLIP expression.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P5875
P698
P921